Drug Detail

Drug Name Etoposide
Trade Name Vepesid
Synonyms EPEG|Eposin
Drug Descriptions

Vepesid (etoposide) binds to and inhibits DNA topoisomerase II, resulting in accumulated DNA damage, inhibition of replication, and cell death (NCI Drug Dictionary).

DrugClasses TOPO2 inhibitor 4

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Therapy Name Drugs Efficacy Evidence Clinical Trials
90Y basiliximab + Basiliximab + Carmustine + Cytarabine + Etoposide + Melphalan 90Y basiliximab Basiliximab Carmustine Cytarabine Etoposide Melphalan 0 1
90Y basiliximab + Carmustine + Cytarabine + Etoposide + Melphalan 90Y basiliximab Carmustine Cytarabine Etoposide Melphalan 0 1
Acalabrutinib + Carboplatin + Etoposide + Ifosfamide + Rituximab Acalabrutinib Carboplatin Etoposide Ifosfamide Rituximab 0 1
Aldoxorubicin + Cisplatin + Cyclophosphamide + Dexamethasone + Etoposide Aldoxorubicin Cisplatin Cyclophosphamide Dexamethasone Etoposide 0 1
Alisertib + Carboplatin + Cyclophosphamide + Etoposide Alisertib Carboplatin Cyclophosphamide Etoposide 0 1
Alisertib + Cisplatin + Etoposide Alisertib Cisplatin Etoposide 0 0
Alisertib + Etoposide Alisertib Etoposide 0 0
Asparaginase + Cyclophosphamide + Etoposide Asparaginase Cyclophosphamide Etoposide 0 1
Atezolizumab + Carboplatin + Etoposide Atezolizumab Carboplatin Etoposide 2 3
Atezolizumab + Carboplatin + Etoposide + Trilaciclib Atezolizumab Carboplatin Etoposide Trilaciclib 0 1
Atovaquone + Cytarabine + Daunorubicin + Etoposide Atovaquone Cytarabine Daunorubicin Etoposide 0 1
Avelumab + Carboplatin + Etoposide + Ifosfamide + Rituximab + Utomilumab Avelumab Carboplatin Etoposide Ifosfamide Rituximab Utomilumab 0 1
Belinostat + Cisplatin + Etoposide Belinostat Cisplatin Etoposide 0 1
Bendamustine + Cytarabine + Etoposide Bendamustine Cytarabine Etoposide 0 1
Bevacizumab + Cisplatin + Etoposide Bevacizumab Cisplatin Etoposide 1 0
Bevacizumab + Cyclophosphamide + Doxorubicin + Etoposide + Ifosfamide + Irinotecan + Sorafenib + Temozolomide + Temsirolimus + Vincristine Bevacizumab Cyclophosphamide Doxorubicin Etoposide Ifosfamide Irinotecan Sorafenib Temozolomide Temsirolimus Vincristine 0 1
BGB-A317 + Cisplatin + Etoposide BGB-A317 Cisplatin Etoposide 0 1
BMS-986012 + Carboplatin + Etoposide BMS-986012 Carboplatin Etoposide 0 1
BMS-986012 + Cisplatin + Etoposide BMS-986012 Cisplatin Etoposide 0 1
Bortezomib + Cytarabine + Etoposide + Midostaurin + Mitoxantrone Bortezomib Cytarabine Etoposide Midostaurin Mitoxantrone 1 0
Buparlisib + Cisplatin + Etoposide Buparlisib Cisplatin Etoposide 0 1
Busulfan + Cyclophosphamide + Etoposide Busulfan Cyclophosphamide Etoposide 0 1
BX-912 + Etoposide BX-912 Etoposide 0 0
Carboplatin + Cisplatin + Doxorubicin + Etoposide Carboplatin Cisplatin Doxorubicin Etoposide 0 1
Carboplatin + Cisplatin + Durvalumab + Etoposide Carboplatin Cisplatin Durvalumab Etoposide 0 2
Carboplatin + Cisplatin + Durvalumab + Etoposide + Tremelimumab Carboplatin Cisplatin Durvalumab Etoposide Tremelimumab 0 2
Carboplatin + Cisplatin + Erlotinib + Etoposide + Paclitaxel Carboplatin Cisplatin Erlotinib Etoposide Paclitaxel 0 1
Carboplatin + Cisplatin + Etoposide Carboplatin Cisplatin Etoposide 0 2
Carboplatin + Cisplatin + Etoposide + Pembrolizumab Carboplatin Cisplatin Etoposide Pembrolizumab 0 1
Carboplatin + Dexamethasone + Etoposide + Ifosfamide + Rituximab Carboplatin Dexamethasone Etoposide Ifosfamide Rituximab 0 1
Carboplatin + Docetaxel + Etoposide + Pembrolizumab Carboplatin Docetaxel Etoposide Pembrolizumab 0 1
Carboplatin + Doxorubicin + Etoposide Carboplatin Doxorubicin Etoposide 0 0
Carboplatin + Durvalumab + Etoposide + Tremelimumab Carboplatin Durvalumab Etoposide Tremelimumab 0 1
Carboplatin + Etoposide Carboplatin Etoposide 0 8
Carboplatin + Etoposide + Ifosfamide Carboplatin Etoposide Ifosfamide 0 6
Carboplatin + Etoposide + Ifosfamide + Lenalidomide + Rituximab Carboplatin Etoposide Ifosfamide Lenalidomide Rituximab 0 1
Carboplatin + Etoposide + Ifosfamide + Nivolumab Carboplatin Etoposide Ifosfamide Nivolumab 0 1
Carboplatin + Etoposide + Ifosfamide + Pembrolizumab Carboplatin Etoposide Ifosfamide Pembrolizumab 0 1
Carboplatin + Etoposide + Ifosfamide + Rituximab Carboplatin Etoposide Ifosfamide Rituximab 0 4
Carboplatin + Etoposide + Ifosfamide + Rituximab + Venetoclax Carboplatin Etoposide Ifosfamide Rituximab Venetoclax 0 1
Carboplatin + Etoposide + Melphalan + Vincristine Carboplatin Etoposide Melphalan Vincristine 0 1
Carboplatin + Etoposide + Nivolumab Carboplatin Etoposide Nivolumab 0 1
Carboplatin + Etoposide + Osimertinib Carboplatin Etoposide Osimertinib 0 1
Carboplatin + Etoposide + Pembrolizumab Carboplatin Etoposide Pembrolizumab 0 4
Carboplatin + Etoposide + Roniciclib Carboplatin Etoposide Roniciclib 1 0
Carboplatin + Etoposide + Veliparib Carboplatin Etoposide Veliparib 0 4
Carboplatin + Etoposide + Vincristine sulfate liposome Carboplatin Etoposide Vincristine sulfate liposome 0 1
Carmustine + Cytarabine + Etoposide + Filgrastim + Lenalidomide + Melphalan + Rituximab Carmustine Cytarabine Etoposide Filgrastim Lenalidomide Melphalan Rituximab 0 1
Carmustine + Cytarabine + Etoposide + Melphalan Carmustine Cytarabine Etoposide Melphalan 0 5
Carmustine + Cytarabine + Etoposide + Melphalan + Rituximab Carmustine Cytarabine Etoposide Melphalan Rituximab 0 1
Carmustine + Cytarabine + Etoposide + Melphalan + Venetoclax Carmustine Cytarabine Etoposide Melphalan Venetoclax 0 2
Celecoxib + Cyclophosphamide + Etoposide + Sirolimus Celecoxib Cyclophosphamide Etoposide Sirolimus 0 1
Cisplatin + Cyclophosphamide + Doxorubicin + Etoposide Cisplatin Cyclophosphamide Doxorubicin Etoposide 0 1
Cisplatin + Cyclophosphamide + Etoposide Cisplatin Cyclophosphamide Etoposide 0 1
Cisplatin + Cyclophosphamide + Etoposide + Vincristine sulfate liposome Cisplatin Cyclophosphamide Etoposide Vincristine sulfate liposome 0 1
Cisplatin + Durvalumab + Etoposide Cisplatin Durvalumab Etoposide 0 1
Cisplatin + Etoposide Cisplatin Etoposide 0 10
Cisplatin + Etoposide + GSK3052230 Cisplatin Etoposide GSK3052230 1 0
Cisplatin + Etoposide + Ipilimumab Cisplatin Etoposide Ipilimumab 0 1
Cisplatin + Etoposide + M7824 Cisplatin Etoposide M7824 0 1
Cisplatin + Etoposide + MSC2490484A Cisplatin Etoposide MSC2490484A 0 1
Cisplatin + Etoposide + Nivolumab Cisplatin Etoposide Nivolumab 0 2
Cisplatin + Etoposide + Osimertinib Cisplatin Etoposide Osimertinib 0 1
Cisplatin + Etoposide + Panobinostat + Radiotherapy Cisplatin Etoposide Panobinostat Radiotherapy 1 0
Cisplatin + Etoposide + Pembrolizumab Cisplatin Etoposide Pembrolizumab 0 4
Cisplatin + Etoposide + Roniciclib Cisplatin Etoposide Roniciclib 0 0
Cisplatin + Etoposide + Rovalpituzumab Tesirine Cisplatin Etoposide Rovalpituzumab Tesirine 0 1
Cisplatin + Etoposide + Sonidegib Cisplatin Etoposide Sonidegib 0 1
Cisplatin + Etoposide + VX-970 Cisplatin Etoposide VX-970 0 1
Clofarabine + Cyclophosphamide + Etoposide Clofarabine Cyclophosphamide Etoposide 0 1
Cyclophosphamide + Cytarabine + Doxorubicin + Etoposide + Filgrastim + Ifosfamide + Leucovorin + Mesna + Methotrexate + Rituximab + Vincristine Cyclophosphamide Cytarabine Doxorubicin Etoposide Filgrastim Ifosfamide Leucovorin Mesna Methotrexate Rituximab Vincristine 0 1
Cyclophosphamide + Doxorubicin + Etoposide + Filgrastim + Ibrutinib + Pegfilgrastim + Prednisone + Rituximab + Vincristine Cyclophosphamide Doxorubicin Etoposide Filgrastim Ibrutinib Pegfilgrastim Prednisone Rituximab Vincristine 0 1
Cyclophosphamide + Doxorubicin + Etoposide + Fludarabine + Prednisone + Rituximab + Vincristine Cyclophosphamide Doxorubicin Etoposide Fludarabine Prednisone Rituximab Vincristine 0 1
Cyclophosphamide + Doxorubicin + Etoposide + Fludarabine + Prednisone + Vincristine Cyclophosphamide Doxorubicin Etoposide Fludarabine Prednisone Vincristine 0 1
Cyclophosphamide + Doxorubicin + Etoposide + Ifosfamide + Vincristine Cyclophosphamide Doxorubicin Etoposide Ifosfamide Vincristine 0 2
Cyclophosphamide + Doxorubicin + Etoposide + Methylprednisolone + Rituximab + Vincristine Cyclophosphamide Doxorubicin Etoposide Methylprednisolone Rituximab Vincristine 0 4
Cyclophosphamide + Doxorubicin + Etoposide + Nivolumab + Prednisone + Rituximab + Vincristine Cyclophosphamide Doxorubicin Etoposide Nivolumab Prednisone Rituximab Vincristine 0 1
Cyclophosphamide + Doxorubicin + Etoposide + Nivolumab + Prednisone + Vincristine Cyclophosphamide Doxorubicin Etoposide Nivolumab Prednisone Vincristine 0 1
Cyclophosphamide + Doxorubicin + Etoposide + Pembrolizumab + Prednisone + Vincristine Cyclophosphamide Doxorubicin Etoposide Pembrolizumab Prednisone Vincristine 0 1
Cyclophosphamide + Doxorubicin + Etoposide + Prednisone + Rituximab + Venetoclax + Vincristine Cyclophosphamide Doxorubicin Etoposide Prednisone Rituximab Venetoclax Vincristine 0 1
Cyclophosphamide + Doxorubicin + Etoposide + Prednisone + Vincristine Cyclophosphamide Doxorubicin Etoposide Prednisone Vincristine 0 1
Cyclophosphamide + Doxorubicin + Etoposide + Vincristine Cyclophosphamide Doxorubicin Etoposide Vincristine 0 2
Cyclophosphamide + Etoposide Cyclophosphamide Etoposide 0 1
Cyclophosphamide + Etoposide + Everolimus + Nelarabine Cyclophosphamide Etoposide Everolimus Nelarabine 0 1
Cyclophosphamide + Etoposide + Topotecan Cyclophosphamide Etoposide Topotecan 0 1
Cytarabine + Daunorubicin + Etoposide Cytarabine Daunorubicin Etoposide 0 2
Cytarabine + Daunorubicin + Etoposide + Mitoxantrone Cytarabine Daunorubicin Etoposide Mitoxantrone 0 0
Cytarabine + Dexamethasone + Etoposide + Ibrutinib + Isavuconazole + Pegylated liposomal-doxorubicin + Rituximab + Temozolomide Cytarabine Dexamethasone Etoposide Ibrutinib Isavuconazole Pegylated liposomal-doxorubicin Rituximab Temozolomide 0 1
Cytarabine + Dexamethasone + Etoposide + Isavuconazole + Pegylated liposomal-doxorubicin + Rituximab + Temozolomide Cytarabine Dexamethasone Etoposide Isavuconazole Pegylated liposomal-doxorubicin Rituximab Temozolomide 0 1
Cytarabine + Etoposide Cytarabine Etoposide 0 2
Cytarabine + Etoposide + Methotrexate Cytarabine Etoposide Methotrexate 0 1
Cytarabine + Etoposide + Mitoxantrone Cytarabine Etoposide Mitoxantrone 0 8
Cytarabine + Etoposide + Mitoxantrone + Prexasertib Cytarabine Etoposide Mitoxantrone Prexasertib 0 1
Cytarabine + Etoposide + Mitoxantrone + Sirolimus Cytarabine Etoposide Mitoxantrone Sirolimus 0 1
Cytarabine + Etoposide + Mitoxantrone + Uproleselan Cytarabine Etoposide Mitoxantrone Uproleselan 0 1
Dactinomycin + Doxorubicin + Etoposide + Ifosfamide + Vincristine Dactinomycin Doxorubicin Etoposide Ifosfamide Vincristine 0 1
Dexamethasone + Etoposide + Ibrutinib + Pegylated liposomal-doxorubicin + Rituximab + Temozolomide Dexamethasone Etoposide Ibrutinib Pegylated liposomal-doxorubicin Rituximab Temozolomide 0 0
Dexamethasone + Etoposide + Ibrutinib + Pegylated liposomal-doxorubicin + Temozolomide Dexamethasone Etoposide Ibrutinib Pegylated liposomal-doxorubicin Temozolomide 0 1
Dexamethasone + Etoposide + Pegylated liposomal-doxorubicin + Rituximab + Temozolomide Dexamethasone Etoposide Pegylated liposomal-doxorubicin Rituximab Temozolomide 0 0
Doxorubicin + Etoposide + Fludarabine + Vincristine Doxorubicin Etoposide Fludarabine Vincristine 0 1
Doxorubicin + Etoposide + Vincristine Doxorubicin Etoposide Vincristine 0 1
Enasidenib + Etoposide + Mitoxantrone Enasidenib Etoposide Mitoxantrone 0 1
Etoposide Etoposide 0 32
Etoposide + Everolimus Etoposide Everolimus 0 0
Etoposide + Filgrastim + Plerixafor Etoposide Filgrastim Plerixafor 0 1
Etoposide + Gemtuzumab ozogamicin + Mitoxantrone Etoposide Gemtuzumab ozogamicin Mitoxantrone 0 1
Etoposide + Ifosfamide Etoposide Ifosfamide 0 2
Etoposide + Ivosidenib + Mitoxantrone Etoposide Ivosidenib Mitoxantrone 0 1
Etoposide + Melphalan Etoposide Melphalan 0 1
Etoposide + NU7441 Etoposide NU7441 1 0
Etoposide + Nutlin-3 Etoposide Nutlin-3 2 0
Etoposide + NVP-ADW742 Etoposide NVP-ADW742 1 0
Etoposide + Temozolomide Etoposide Temozolomide 0 1
Etoposide + Vorinostat Etoposide Vorinostat 0 1
Etoposide + YU238259 Etoposide YU238259 1 0