Drug Detail

Drug Name Etoposide
Trade Name Vepesid
Synonyms EPEG|Eposin
Drug Descriptions

Vepesid (etoposide) binds to and inhibits DNA topoisomerase II, resulting in accumulated DNA damage, inhibition of replication, and cell death (NCI Drug Dictionary).

DrugClasses TOPO2 inhibitor 4

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Therapy Name Therapy Description
Vincristine + Doxorubicin + Cyclophosphamide + Ifosfamide + Etoposide
Bevacizumab + Cisplatin + Etoposide
Cisplatin + Etoposide + Panobinostat + Radiotherapy
Venetoclax + DA-EPOCH-R
Carboplatin + Etoposide + Veliparib
R2-ICE
Cisplatin + Etoposide + M7824 M7824 is a human PD-L1 (CD274) antibody fused with transforming growth factor-beta (TGF-beta, TGFBR2) receptor II extracellular domain, which blocks two immuno-inhibitory pathways simultaneously, therefore enhances anti-tumor immunity (PMID: 29298798).
Etoposide Vepesid (etoposide) binds to and inhibits DNA topoisomerase II, resulting in accumulated DNA damage, inhibition of replication, and cell death (NCI Drug Dictionary).
BEAM + Lenalidomide + Filgrastim + Rituximab
Cytarabine + Etoposide + Mitoxantrone + Prexasertib Prexasertib (LY2606368) inhibits checkpoint kinase 1 (Chk1), which may result in accumulation of DNA damage and decreased tumor growth (PMID: 26141948, PMID: 28270495).
Acalabrutinib + Carboplatin + Etoposide + Ifosfamide + Rituximab
Mitoxantrone + Etoposide + Cytarabine
Alisertib + Etoposide
Carboplatin + Etoposide + Roniciclib
Doxorubicin + Etoposide + Vincristine
Celecoxib + Cyclophosphamide + Etoposide + Sirolimus
Temozolomide + Etoposide + Doxil + Dexamethasone + Ibrutinib
Vincristine + Doxorubicin + Cyclophosphamide + Ifosfamide + Etoposide + others
BGB-A317 + Cisplatin + Etoposide
Doxorubicin + Etoposide + Fludarabine + Vincristine
Nivolumab + Etoposide + Ifosfamide + Carboplatin
Cyclophosphamide + Etoposide + Everolimus + Nelarabine
Rituximab + Fludarabine + EPOCH
Etoposide + Melphalan
Etoposide + NU7441
Belinostat + Cisplatin + Etoposide
Cytarabine + Etoposide + Methotrexate
Carboplatin + Doxorubicin + Etoposide
Carboplatin + Cisplatin + Etoposide
Asparaginase + Cyclophosphamide + Etoposide
Carboplatin + Etoposide + Pembrolizumab
Cisplatin + Etoposide + Osimertinib
Cisplatin + Etoposide + Nivolumab
Fludarabine + EPOCH
Busulfan + Cyclophosphamide + Etoposide
Aldoxorubicin + Cisplatin + Cyclophosphamide + Dexamethasone + Etoposide
Carmustine + Cytarabine + Etoposide + Melphalan
Cisplatin + Etoposide + GSK3052230
Basiliximab + 90Y basiliximab + Carmustine + Cytarbine + Etoposide + Melphalan
Carboplatin + Dexamethasone + Etoposide + Ifosfamide + Rituximab
BMS-986012 + Cisplatin + Etoposide
Pembrolizumab + Etoposide + Carboplatin + Ifosfamide
Carboplatin + Etoposide + Osimertinib
Cisplatin + Doxorubicin + Cyclophosphamide + Etoposide
R-da-EPOCH
EPOCH
Clofarabine + Etoposide + Cyclophosphamide
MSC2490484A + Cisplatin + Etoposide
Cytarabine + Daunorubicin + Etoposide
Nutlin-3 + Etoposide
Carboplatin + Docetaxel + Etoposide + Pembrolizumab
Cisplatin + Etoposide
Cisplatin + Etoposide + Pembrolizumab
Carboplatin + Etoposide + Ifosfamide + Rituximab
Rovalpituzumab Tesirine + Cisplatin + Etoposide
Cisplatin + Etoposide + Ipilimumab
Etoposide + Everolimus
BMS-986012 + Carboplatin + Etoposide
Etoposide + Ifosfamide
Nivolumab + REPOCH
Etoposide + Filgrastim + Plerixafor
R-EPOCH
Carboplatin + Etoposide + Nivolumab
Bendamustine + Cytarabine + Etoposide
Cytarabine + Etoposide
Cisplatin + Etoposide + Paclitaxel + Carboplatin + Erlotinib
Cyclophosphamide + Doxorubicin + Etoposide + Vincristine
Temozolomide + Etoposide
MEDI4736 + Tremelimumab + Carboplatin + Cisplatin + Etoposide
Bortezomib + Midostaurin + MEC
Carboplatin + Cisplatin + Etoposide + Pembrolizumab
Alisertib + Cisplatin + Etoposide
Cisplatin + Durvalumab + Etoposide
EPOCH + Nivolumab
Etoposide + NVP-ADW742
BX-912 + Etoposide
Atezolizumab + Carboplatin + Etoposide
Vorinostat + Etoposide
Carboplatin + Etoposide
Carboplatin + Etoposide + Melphalan + Vincristine
Atezolizumab + Carboplatin + Etoposide + Trilaciclib
Etoposide + Gemtuzumab ozogamicin + Mitoxantrone Mylotarg (gemtuzumab ozogamicin) is an antibody-drug conjugate comprising an anti-CD33 antibody linked to the cytotoxic agent calicheamicin, which results in DNA damage in CD33-expressing tumor cells (PMID: 28607471). Mylotarg (gemtuzumab ozogamicin) is FDA approved for CD33-positive acute myeloid leukemia (FDA.gov).
Cytarabine + Daunorubicin + Etoposide + Mitoxantrone
Carboplatin + Cisplatin + Durvalumab + Etoposide
Carmustine + Cytarabine + Etoposide + Melphalan + Rituximab
Vincristine + Doxorubicin + Dactinomycin + Ifosfamide + Etoposide
Cisplatin + Etoposide + Sonidegib
Etoposide + YU238259
Avelumab + Utomilumab + Carboplatin + Etoposide + Ifosfamide + Rituximab
Carboplatin + Etoposide + Ifosfamide
Cyclophosphamide + Etoposide
Cytarabine + Etoposide + Mitoxantrone + Uproleselan
R-MACLO/IVAM
BKM120 + Etoposide + Cisplatin
Atovaquone + Cytarabine + Daunorubicin + Etoposide
COPDAC-28 + Pembrolizumab
Cisplatin + Etoposide + Roniciclib
Venetoclax + Rituximab + Ifosfamide + Carboplatin + Etoposide
Carmustine + Cytarabine + Etoposide + Melphalan + Venetoclax
Cyclophosphamide + Etoposide + Topotecan