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Drug Name Mosunetuzumab
Trade Name
Synonyms RG7828|BTCT4465A|RO7030816|BTCT-4465A
Drug Descriptions

Mosunetuzumab (BTCT4465A) is a bispecific antibody targeting CD20 and CD3, which results in killing of CD20-positive tumor cells (PMID: 25972002, PMID: 29351372)

DrugClasses CD20 Antibody 14
CAS Registry Number 1905409-39-3
NCIT ID C129691

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Atezolizumab + Mosunetuzumab Atezolizumab Mosunetuzumab 0 1
Atezolizumab + Mosunetuzumab + Tiragolumab + Tocilizumab Atezolizumab Mosunetuzumab Tiragolumab Tocilizumab 0 1
Cyclophosphamide + Doxorubicin + Mosunetuzumab + Polatuzumab vedotin-piiq + Prednisone Cyclophosphamide Doxorubicin Mosunetuzumab Polatuzumab vedotin-piiq Prednisone 0 1
Cyclophosphamide + Doxorubicin + Mosunetuzumab + Prednisone + Vincristine Sulfate Cyclophosphamide Doxorubicin Mosunetuzumab Prednisone Vincristine Sulfate 0 1
Lenalidomide + Mosunetuzumab Lenalidomide Mosunetuzumab 0 2
Lenalidomide + Mosunetuzumab + Tocilizumab Lenalidomide Mosunetuzumab Tocilizumab 0 1
Mosunetuzumab Mosunetuzumab 0 2
Mosunetuzumab + Obinutuzumab + Polatuzumab vedotin-piiq Mosunetuzumab Obinutuzumab Polatuzumab vedotin-piiq 0 1
Mosunetuzumab + Polatuzumab vedotin-piiq Mosunetuzumab Polatuzumab vedotin-piiq 0 3
Mosunetuzumab + Polatuzumab vedotin-piiq + Tocilizumab Mosunetuzumab Polatuzumab vedotin-piiq Tocilizumab 0 1
Mosunetuzumab + Tiragolumab + Tocilizumab Mosunetuzumab Tiragolumab Tocilizumab 0 1
Mosunetuzumab + Tocilizumab Mosunetuzumab Tocilizumab 0 3


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