Drug Detail


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Drug Name Tocilizumab
Trade Name Actemra
Synonyms Atlizumab
Drug Descriptions

Actemra (tocilizumab) is a humamized monoclonal antibody that targets IL-6R, resulting in decreased downstream signaling and potentially resulted in decreased tumor growth and progression (PMID: 26751841, PMID: 25658637). Actemra (tocilizumab) is FDA approved for use in treating rheumatoid arthritis, polyarticular juvenile idiopathic arthritis, and systemic juvenile idiopathic arthritis (FDA.gov).

CAS Registry Number 375823-41-9
NCIT ID C84217


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Atezolizumab + Bevacizumab + Tocilizumab Atezolizumab Bevacizumab Tocilizumab 0 1
Atezolizumab + Obinutuzumab + RO7082859 + Tocilizumab Atezolizumab Obinutuzumab RO7082859 Tocilizumab 0 1
Atezolizumab + Tocilizumab Atezolizumab Tocilizumab 0 3
BFCR4350A + Tocilizumab BFCR4350A Tocilizumab 0 1
BTCT4465A + Lenalidomide + Tocilizumab BTCT4465A Lenalidomide Tocilizumab 0 1
BTCT4465A + Tocilizumab BTCT4465A Tocilizumab 0 2
Dasatinib + RO7283420 + Tocilizumab Dasatinib RO7283420 Tocilizumab 0 1
Ipilimumab + Nivolumab + Tocilizumab Ipilimumab Nivolumab Tocilizumab 0 2
Lenalidomide + Rituximab + Tocilizumab Lenalidomide Rituximab Tocilizumab 0 1
Nivolumab + Tocilizumab Nivolumab Tocilizumab 0 1
Obinutuzumab + Polatuzumab vedotin-piiq + RO7082859 + Tocilizumab Obinutuzumab Polatuzumab vedotin-piiq RO7082859 Tocilizumab 0 1
Obinutuzumab + RO7082859 + RO7227166 + Tocilizumab Obinutuzumab RO7082859 RO7227166 Tocilizumab 0 1
Obinutuzumab + RO7082859 + Tocilizumab Obinutuzumab RO7082859 Tocilizumab 0 1
Obinutuzumab + RO7227166 + Tocilizumab Obinutuzumab RO7227166 Tocilizumab 0 1
Obinutuzumab + RO7293583 + Tocilizumab Obinutuzumab RO7293583 Tocilizumab 0 1
Pertuzumab + Tocilizumab + Trastuzumab Pertuzumab Tocilizumab Trastuzumab 0 1
RO7119929 + Tocilizumab RO7119929 Tocilizumab 0 1
RO7293583 + Tocilizumab RO7293583 Tocilizumab 0 1
RO7444973 + Tocilizumab RO7444973 Tocilizumab 0 1
Tocilizumab Tocilizumab 0 9

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