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Drug Name Tiragolumab
Trade Name
Synonyms RO7092284|RG6058|MTIG7192A
Drug Descriptions

Tiragolumab (MTIG7192A) is an anti-human TIGIT (T cell immunoreceptor with Ig ITIM domain) antibody that potentially has anti-tumor activities through modulating the immune response to tumors (PMID: 29991503, PMID: 32576590).

DrugClasses Immune Checkpoint Inhibitor 148 TIGIT Antibody 15
CAS Registry Number 1918185-84-8
NCIT ID C131291

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Atezolizumab + Bevacizumab + Tiragolumab Atezolizumab Bevacizumab Tiragolumab 0 2
Atezolizumab + Carboplatin + Etoposide + Tiragolumab Atezolizumab Carboplatin Etoposide Tiragolumab 0 1
Atezolizumab + Carboplatin + Gemcitabine + Tiragolumab Atezolizumab Carboplatin Gemcitabine Tiragolumab 0 1
Atezolizumab + Carboplatin + Paclitaxel + Tiragolumab Atezolizumab Carboplatin Paclitaxel Tiragolumab 0 2
Atezolizumab + Carboplatin + Pemetrexed Disodium + Tiragolumab Atezolizumab Carboplatin Pemetrexed Disodium Tiragolumab 0 2
Atezolizumab + Cisplatin + Fluorouracil + Tiragolumab Atezolizumab Cisplatin Fluorouracil Tiragolumab 0 1
Atezolizumab + Cisplatin + Gemcitabine + Tiragolumab Atezolizumab Cisplatin Gemcitabine Tiragolumab 0 1
Atezolizumab + Cisplatin + Pemetrexed Disodium + Tiragolumab Atezolizumab Cisplatin Pemetrexed Disodium Tiragolumab 0 2
Atezolizumab + Cyclophosphamide + Doxorubicin + Filgrastim + Tiragolumab Atezolizumab Cyclophosphamide Doxorubicin Filgrastim Tiragolumab 0 1
Atezolizumab + Cyclophosphamide + Doxorubicin + Pegfilgrastim + Tiragolumab Atezolizumab Cyclophosphamide Doxorubicin Pegfilgrastim Tiragolumab 0 1
Atezolizumab + Cyclophosphamide + Doxorubicin + Sargramostim + Tiragolumab Atezolizumab Cyclophosphamide Doxorubicin Sargramostim Tiragolumab 0 1
Atezolizumab + Mosunetuzumab + Tiragolumab + Tocilizumab Atezolizumab Mosunetuzumab Tiragolumab Tocilizumab 0 1
Atezolizumab + Nab-paclitaxel + Tiragolumab Atezolizumab Nab-paclitaxel Tiragolumab 0 1
Atezolizumab + Pemetrexed Disodium + Tiragolumab Atezolizumab Pemetrexed Disodium Tiragolumab 0 1
Atezolizumab + Tiragolumab Atezolizumab Tiragolumab 0 14
Daratumumab + Tiragolumab Daratumumab Tiragolumab 0 1
Mosunetuzumab + Tiragolumab + Tocilizumab Mosunetuzumab Tiragolumab Tocilizumab 0 1
Rituximab + Tiragolumab Rituximab Tiragolumab 0 1
RO7247669 + Tiragolumab RO7247669 Tiragolumab 0 1
Tiragolumab Tiragolumab 0 3


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