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Drug Name Axitinib
Trade Name Inlyta
Synonyms AG-013736
Drug Descriptions

Inlyta (axitinib) inhibits the VEGFRs, PDGFR, and KIT, potentially resulting in decreased angiogenesis and reduced tumor growth (PMID: 16027439, PMID: 25709499). Inlyta (axitinib) is approved for renal cell carcinoma (FDA.gov).

DrugClasses KIT Inhibitor 50 PDGFR Inhibitor (Pan) 27 VEGFR Inhibitor (Pan) 32

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Avelumab + Axitinib Avelumab Axitinib 1 5
Avelumab + Axitinib + Palbociclib Avelumab Axitinib Palbociclib 0 1
Axitinib Axitinib 24 24
Axitinib + AZD0156 AZD0156 Axitinib 0 0
Axitinib + Bevacizumab Axitinib Bevacizumab 1 0
Axitinib + Bosutinib Axitinib Bosutinib 0 1
Axitinib + Carboplatin + Paclitaxel Axitinib Carboplatin Paclitaxel 1 0
Axitinib + Carotuximab Axitinib Carotuximab 1 1
Axitinib + Crizotinib Axitinib Crizotinib 0 1
Axitinib + Dalantercept Axitinib Dalantercept 1 1
Axitinib + Fluorouracil + Irinotecan + Leucovorin Axitinib Fluorouracil Irinotecan Leucovorin 1 0
Axitinib + Fluorouracil + Leucovorin + Oxaliplatin Axitinib Fluorouracil Leucovorin Oxaliplatin 1 0
Axitinib + Gemcitabine Axitinib Gemcitabine 1 0
Axitinib + Nivolumab Axitinib Nivolumab 0 3
Axitinib + Osimertinib Axitinib Osimertinib 0 0
Axitinib + Pembrolizumab Axitinib Pembrolizumab 1 5
Axitinib + PF-04518600 Axitinib PF-04518600 0 1
Axitinib + Radiotherapy Axitinib Radiotherapy 1 0
Axitinib + Selenomethionine Axitinib Selenomethionine 0 1
Axitinib + Talazoparib Axitinib Talazoparib 0 1
Axitinib + X4P-001 Axitinib X4P-001 1 0


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