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Drug Name NKTR-214
Trade Name
Synonyms Bempegaldesleukin|Bempeg
Drug Descriptions

Bempegaldesleukin (NKTR-214) comprises IL2 bound to polyethylene glycol, which stimulates anti-tumor immune response, potentially resulting in decreased tumor growth (PMID: 26832745, PMID: 32723187).

CAS Registry Number 1939126-74-5
NCIT ID C131019


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Avelumab + Enzalutamide + NKTR-214 Avelumab Enzalutamide NKTR-214 0 1
Avelumab + NKTR-214 Avelumab NKTR-214 0 1
Avelumab + NKTR-214 + Talazoparib Avelumab NKTR-214 Talazoparib 0 1
Axitinib + Nivolumab + NKTR-214 Axitinib NKTR-214 Nivolumab 0 1
Carboplatin + Nab-paclitaxel + NKTR-214 + Pembrolizumab Carboplatin NKTR-214 Nab-paclitaxel Pembrolizumab 0 1
Carboplatin + NKTR-214 + Paclitaxel + Pembrolizumab Carboplatin NKTR-214 Paclitaxel Pembrolizumab 0 1
Carboplatin + NKTR-214 + Pembrolizumab + Pemetrexed Disodium Carboplatin NKTR-214 Pembrolizumab Pemetrexed Disodium 0 1
Cisplatin + NKTR-214 + Pembrolizumab Cisplatin NKTR-214 Pembrolizumab 0 1
Mivavotinib + NKTR-214 Mivavotinib NKTR-214 0 1
Nivolumab + NKTR-214 NKTR-214 Nivolumab 0 10
Nivolumab + NKTR-214 + NKTR-262 NKTR-214 NKTR-262 Nivolumab 0 1
Nivolumab + NKTR-214 + XL092 NKTR-214 Nivolumab XL092 0 1
NKTR-214 NKTR-214 0 1
NKTR-214 + NKTR-262 NKTR-214 NKTR-262 0 1
NKTR-214 + Pembrolizumab NKTR-214 Pembrolizumab 0 3
NKTR-214 + unspecified PD-1 antibody NKTR-214 unspecified PD-1 antibody 0 0
NKTR-214 + VB10.NEO NKTR-214 VB10.NEO 0 0

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