Drug Detail


Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name XL092
Trade Name
Synonyms XL-092|XL 092
Drug Descriptions

XL092 is a receptor tyrosine kinase inhibitor that targets MET and other kinases and also prevents angiogenesis through inhibition of VEGF receptor subtypes (NCI Drug Dictionary).

DrugClasses MET Inhibitor 56 VEGFR Inhibitor (Pan) 33
CAS Registry Number 2367004-54-2
NCIT ID C161598


  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"


  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Atezolizumab + XL092 Atezolizumab XL092 0 1
Ipilimumab + Nivolumab + XL092 Ipilimumab Nivolumab XL092 0 1
Nivolumab + NKTR-214 + XL092 NKTR-214 Nivolumab XL092 0 1
Nivolumab + XL092 Nivolumab XL092 0 1
XL092 XL092 0 2

Additional content available in CKB BOOST