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Drug Name Pemetrexed
Trade Name Alimta
Synonyms LY231514
Drug Descriptions

Alimta (pemetrexed) is an antifolate, which inhibits thymidylate synthase (NCI Drug Dictionary).

DrugClasses Chemotherapy - Antimetabolite 11

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Therapy Name Drugs Efficacy Evidence Clinical Trials
AB928 + Carboplatin + Pembrolizumab + Pemetrexed AB928 Carboplatin Pembrolizumab Pemetrexed 0 1
AB928 + Carboplatin + Pemetrexed AB928 Carboplatin Pemetrexed 0 1
Abemaciclib + Pemetrexed Abemaciclib Pemetrexed 1 0
ADI-PEG 20 + Cisplatin + Pemetrexed ADI-PEG 20 Cisplatin Pemetrexed 0 1
Anetumab ravtansine + Cisplatin + Pemetrexed Anetumab ravtansine Cisplatin Pemetrexed 0 1
Atezolizumab + Bevacizumab + Carboplatin + Pemetrexed Atezolizumab Bevacizumab Carboplatin Pemetrexed 0 2
Atezolizumab + Carboplatin + Cisplatin + Nab-paclitaxel + Pemetrexed Atezolizumab Carboplatin Cisplatin Nab-paclitaxel Pemetrexed 0 1
Atezolizumab + Carboplatin + Pemetrexed Atezolizumab Carboplatin Pemetrexed 0 2
Atezolizumab + Cisplatin + Pemetrexed Atezolizumab Cisplatin Pemetrexed 0 2
Avelumab + Carboplatin + Pemetrexed Avelumab Carboplatin Pemetrexed 0 1
Avelumab + Pemetrexed Avelumab Pemetrexed 0 1
AZD9150 + Durvalumab + Pemetrexed AZD9150 Durvalumab Pemetrexed 0 0
Bevacizumab + Carboplatin + Pemetrexed Bevacizumab Carboplatin Pemetrexed 0 1
Bevacizumab + Pemetrexed Bevacizumab Pemetrexed 0 1
Binimetinib + Carboplatin + Pemetrexed Binimetinib Carboplatin Pemetrexed 0 1
Bosutinib + Pemetrexed Bosutinib Pemetrexed 0 1
Buparlisib + Carboplatin + Pemetrexed Buparlisib Carboplatin Pemetrexed 0 1
Cabozantinib + Pemetrexed Cabozantinib Pemetrexed 0 1
Carboplatin + Cemiplimab + Pemetrexed Carboplatin Cemiplimab Pemetrexed 0 1
Carboplatin + Cisplatin + Docetaxel + Gemcitabine + Pemetrexed + Vinorelbine Carboplatin Cisplatin Docetaxel Gemcitabine Pemetrexed Vinorelbine 0 1
Carboplatin + Cisplatin + Durvalumab + Pemetrexed Carboplatin Cisplatin Durvalumab Pemetrexed 0 1
Carboplatin + Cisplatin + Epacadostat + Gemcitabine + Nivolumab + Paclitaxel + Pemetrexed Carboplatin Cisplatin Epacadostat Gemcitabine Nivolumab Paclitaxel Pemetrexed 0 1
Carboplatin + Cisplatin + Gemcitabine + Nivolumab + Paclitaxel + Pemetrexed Carboplatin Cisplatin Gemcitabine Nivolumab Paclitaxel Pemetrexed 0 1
Carboplatin + Cisplatin + Gemcitabine + Paclitaxel + Pemetrexed Carboplatin Cisplatin Gemcitabine Paclitaxel Pemetrexed 0 1
Carboplatin + Cisplatin + Gemcitabine + Pemetrexed + Vinorelbine Carboplatin Cisplatin Gemcitabine Pemetrexed Vinorelbine 0 1
Carboplatin + Cisplatin + Nab-paclitaxel + Pemetrexed Carboplatin Cisplatin Nab-paclitaxel Pemetrexed 0 1
Carboplatin + Cisplatin + Nivolumab + Paclitaxel + Pemetrexed Carboplatin Cisplatin Nivolumab Paclitaxel Pemetrexed 0 1
Carboplatin + Cisplatin + Paclitaxel + Pemetrexed Carboplatin Cisplatin Paclitaxel Pemetrexed 0 2
Carboplatin + Cisplatin + Pembrolizumab + Pemetrexed Carboplatin Cisplatin Pembrolizumab Pemetrexed 0 1
Carboplatin + Cisplatin + Pemetrexed Carboplatin Cisplatin Pemetrexed 0 4
Carboplatin + Cisplatin + Pemetrexed + Spartalizumab Carboplatin Cisplatin Pemetrexed Spartalizumab 0 1
Carboplatin + Demcizumab + Pemetrexed Carboplatin Demcizumab Pemetrexed 1 0
Carboplatin + Durvalumab + Pemetrexed Carboplatin Durvalumab Pemetrexed 0 4
Carboplatin + Epacadostat + Pembrolizumab + Pemetrexed Carboplatin Epacadostat Pembrolizumab Pemetrexed 0 1
Carboplatin + Gefitinib + Pemetrexed Carboplatin Gefitinib Pemetrexed 0 0
Carboplatin + INCMGA00012 + Pemetrexed Carboplatin INCMGA00012 Pemetrexed 0 2
Carboplatin + L-DOS47 + Pemetrexed Carboplatin L-DOS47 Pemetrexed 0 1
Carboplatin + Lenvatinib + Pembrolizumab + Pemetrexed Carboplatin Lenvatinib Pembrolizumab Pemetrexed 0 1
Carboplatin + LY2090314 + Pemetrexed Carboplatin LY2090314 Pemetrexed 1 0
Carboplatin + M7824 + Pemetrexed Carboplatin M7824 Pemetrexed 0 1
Carboplatin + MEDI5752 + Pemetrexed Carboplatin MEDI5752 Pemetrexed 0 1
Carboplatin + Metformin + Pemetrexed Carboplatin Metformin Pemetrexed 0 0
Carboplatin + MK-7684 + Pembrolizumab + Pemetrexed Carboplatin MK-7684 Pembrolizumab Pemetrexed 0 1
Carboplatin + NEO-PV-01 + Pembrolizumab + Pemetrexed + Poly ICLC Carboplatin NEO-PV-01 Pembrolizumab Pemetrexed Poly ICLC 0 1
Carboplatin + Nivolumab + Paclitaxel + Pemetrexed + Veliparib Carboplatin Nivolumab Paclitaxel Pemetrexed Veliparib 0 1
Carboplatin + Nivolumab + Pemetrexed Carboplatin Nivolumab Pemetrexed 0 2
Carboplatin + Osimertinib + Pemetrexed Carboplatin Osimertinib Pemetrexed 0 1
Carboplatin + Paclitaxel + Pembrolizumab + Pemetrexed Carboplatin Paclitaxel Pembrolizumab Pemetrexed 0 1
Carboplatin + Paclitaxel + Pemetrexed + Veliparib Carboplatin Paclitaxel Pemetrexed Veliparib 0 1
Carboplatin + Pembrolizumab + Pemetrexed Carboplatin Pembrolizumab Pemetrexed 0 10
Carboplatin + Pembrolizumab + Pemetrexed + Rucaparib Carboplatin Pembrolizumab Pemetrexed Rucaparib 0 1
Carboplatin + Pemetrexed Carboplatin Pemetrexed 0 21
Cediranib + Cisplatin + Pemetrexed Cediranib Cisplatin Pemetrexed 0 1
Cisplatin + Durvalumab + Pemetrexed Cisplatin Durvalumab Pemetrexed 0 6
Cisplatin + INCMGA00012 + Pemetrexed Cisplatin INCMGA00012 Pemetrexed 0 2
Cisplatin + Ipilimumab + Pemetrexed Cisplatin Ipilimumab Pemetrexed 0 1
Cisplatin + Lenvatinib + Pembrolizumab + Pemetrexed Cisplatin Lenvatinib Pembrolizumab Pemetrexed 0 1
Cisplatin + LY2603618 + Pemetrexed Cisplatin LY2603618 Pemetrexed 1 0
Cisplatin + M7824 + Pemetrexed Cisplatin M7824 Pemetrexed 0 2
Cisplatin + MLN4924 + Pemetrexed Cisplatin MLN4924 Pemetrexed 0 1
Cisplatin + Necitumumab + Pemetrexed Cisplatin Necitumumab Pemetrexed 1 0
Cisplatin + Nivolumab + Pemetrexed Cisplatin Nivolumab Pemetrexed 0 2
Cisplatin + Osimertinib + Pemetrexed Cisplatin Osimertinib Pemetrexed 0 1
Cisplatin + Pembrolizumab + Pemetrexed Cisplatin Pembrolizumab Pemetrexed 0 9
Cisplatin + Pemetrexed Cisplatin Pemetrexed 0 23
Cisplatin + Pemetrexed + Ruxolitinib Cisplatin Pemetrexed Ruxolitinib 0 1
Cisplatin + Pemetrexed + Spartalizumab Cisplatin Pemetrexed Spartalizumab 0 1
Crizotinib + Pazopanib + Pemetrexed Crizotinib Pazopanib Pemetrexed 0 1
Crizotinib + Pemetrexed Crizotinib Pemetrexed 0 2
Docetaxel + Gemcitabine + Pemetrexed Docetaxel Gemcitabine Pemetrexed 0 1
Docetaxel + Irinotecan + Pemetrexed Docetaxel Irinotecan Pemetrexed 0 1
Docetaxel + Pemetrexed Docetaxel Pemetrexed 0 1
Durvalumab + Oleclumab + Pemetrexed Durvalumab Oleclumab Pemetrexed 0 0
Durvalumab + Pemetrexed Durvalumab Pemetrexed 0 1
Erlotinib + Pemetrexed Erlotinib Pemetrexed 0 3
Gefitinib + Pemetrexed Gefitinib Pemetrexed 0 0
Gemcitabine + Pemetrexed Gemcitabine Pemetrexed 0 1
INCMGA00012 + Pemetrexed INCMGA00012 Pemetrexed 0 1
Itraconazole + Pemetrexed Itraconazole Pemetrexed 1 0
Luminespib + Pemetrexed Luminespib Pemetrexed 0 1
LY2603618 + Pemetrexed LY2603618 Pemetrexed 1 0
MEDI5117 + Pemetrexed MEDI5117 Pemetrexed 0 0
Nivolumab + Pemetrexed Nivolumab Pemetrexed 0 2
Osimertinib + Pemetrexed Osimertinib Pemetrexed 0 1
Oxaliplatin + Pembrolizumab + Pemetrexed Oxaliplatin Pembrolizumab Pemetrexed 0 1
Pazopanib + Pemetrexed Pazopanib Pemetrexed 0 1
Pelareorep + Pemetrexed Pelareorep Pemetrexed 0 1
Pembrolizumab + Pemetrexed Pembrolizumab Pemetrexed 0 7
Pemetrexed Pemetrexed 0 37
Pemetrexed + Prexasertib Pemetrexed Prexasertib 0 1
Pemetrexed + Sirolimus Pemetrexed Sirolimus 1 0
Pemetrexed + Sorafenib Pemetrexed Sorafenib 3 2
Pemetrexed + Tislelizumab Pemetrexed Tislelizumab 0 1
Pemetrexed + Trametinib Pemetrexed Trametinib 1 1


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