Drug Detail


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Drug Name RGX-104
Trade Name
Synonyms RGX104|RGX 104
Drug Descriptions

RGX-104 activates liver-X nuclear hormone receptor (LXR), resulting in ApoE expression and enhancement of antitumor immunity (Mol Cancer Ther 2018;17(1 Suppl):Abstract nr B001, PMID: 32448508).

CAS Registry Number 610318-03-1
NCIT ID C131910


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Carboplatin + Durvalumab + Nab-paclitaxel + Pemetrexed Disodium + RGX-104 Carboplatin Durvalumab Nab-paclitaxel Pemetrexed Disodium RGX-104 0 1
Carboplatin + Pembrolizumab + Pemetrexed Disodium + RGX-104 Carboplatin Pembrolizumab Pemetrexed Disodium RGX-104 0 1
Docetaxel + RGX-104 Docetaxel RGX-104 0 0
Ipilimumab + RGX-104 Ipilimumab RGX-104 0 1
Nivolumab + RGX-104 Nivolumab RGX-104 0 1
RGX-104 RGX-104 0 1

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