Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name Pirfenidone
Trade Name
Synonyms Deskar
Drug Descriptions

Pirfenidone is an antifibrotic agent, which potentially activates BMP pathway, and inhibits AKT and MAPK downstream signaling, thereby reducing the proliferation and migration of tumor cells (Cancer Res 2018;78(13 Suppl):Abstract nr LB-014).

DrugClasses
CAS Registry Number 53179-13-8
NCIT ID C2635

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Atezolizumab + Pirfenidone Atezolizumab Pirfenidone 0 1
Carboplatin + Paclitaxel + Pirfenidone Carboplatin Paclitaxel Pirfenidone 0 1
Carboplatin + Pemetrexed Disodium + Pirfenidone Carboplatin Pemetrexed Disodium Pirfenidone 0 1
Cisplatin + Pirfenidone Cisplatin Pirfenidone 0 0
Pirfenidone Pirfenidone 0 0


Additional content available in CKB BOOST