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Drug Name Pirfenidone
Trade Name
Synonyms Deskar
Drug Descriptions

Pirfenidone is an antifibrotic agent, which potentially activates BMP pathway, and inhibits AKT and MAPK downstream signaling, thereby reducing the proliferation and migration of tumor cells (Cancer Res 2018;78(13 Suppl):Abstract nr LB-014).

DrugClasses
CAS Registry Number 53179-13-8
NCIT ID C2635

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Atezolizumab + Pirfenidone Atezolizumab Pirfenidone 0 1
Carboplatin + Paclitaxel + Pirfenidone Carboplatin Paclitaxel Pirfenidone 0 1
Carboplatin + Pemetrexed Disodium + Pirfenidone Carboplatin Pemetrexed Disodium Pirfenidone 0 1
Cisplatin + Pirfenidone Cisplatin Pirfenidone 0 0
Pirfenidone Pirfenidone 0 0


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