Drug Detail


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Drug Name IPH5201
Trade Name
Synonyms IPH-5201|IPH 5201|IPH52
Drug Descriptions

IPH5201 is a monoclonal antibody that binds to and inhibits soluble and membrane-bound CD39, resulting in decreased ATP hydrolysis, which potentially leads to activation of T-lymphocytes and anti-tumor immune response (PMID: 31116985, PMID: 31244820).

DrugClasses Adenosine Targeting 23 CD39 Antibody 5
CAS Registry Number NA
NCIT ID C175591


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Carboplatin + Durvalumab + IPH5201 + Paclitaxel Carboplatin Durvalumab IPH5201 Paclitaxel 0 1
Carboplatin + Durvalumab + IPH5201 + Pemetrexed Disodium Carboplatin Durvalumab IPH5201 Pemetrexed Disodium 0 1
Cisplatin + Durvalumab + IPH5201 + Pemetrexed Disodium Cisplatin Durvalumab IPH5201 Pemetrexed Disodium 0 1
Durvalumab + IPH5201 Durvalumab IPH5201 0 1
Durvalumab + IPH5201 + Oleclumab Durvalumab IPH5201 Oleclumab 0 1
IPH5201 IPH5201 0 1

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