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Drug Name Zanubrutinib
Trade Name Brukinsa
Synonyms BGB-3111
Drug Descriptions

Brukinsa (zanubrutinib) inhibits Bruton tyrosine kinase (BTK), leading to decreased B-cell activation and reduced growth of BTK over-expressing cells (PMID: 31378456). Brukinsa (zanubrutinib) is FDA approved for use in patients with mantle cell lymphoma (FDA.gov).

DrugClasses BTK inhibitor 22

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Obinutuzumab + Venetoclax + Zanubrutinib Obinutuzumab Venetoclax Zanubrutinib 0 1
Obinutuzumab + Zanubrutinib Obinutuzumab Zanubrutinib 0 2
Rituximab + Zanubrutinib Rituximab Zanubrutinib 0 2
Zanubrutinib Zanubrutinib 4 8


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