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Drug Name Bendamustine
Trade Name Treanda
Synonyms Ribomustin|SyB L-0501|SDX-105
Drug Descriptions

Treanda (bendamustine) is an alkylating agent with unique mechanisms, resulting in increased DNA damage and base-excision DNA repair pathway induction, and potentially leading to decreased growth of tumors, including those resistant to other alkylating agents (PMID: 18172283, PMID: 19117340, PMID: 19224851). Treanda (bendamustine) is FDA approved for use in chronic lymphocytic leukemia and indolent non-Hodgkin lymphoma (FDA.gov).

DrugClasses Chemotherapy - Alkylating 14

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Acalabrutinib + Bendamustine + Cytarabine + Rituximab Acalabrutinib Bendamustine Cytarabine Rituximab 0 2
Acalabrutinib + Bendamustine + Rituximab Acalabrutinib Bendamustine Rituximab 0 3
Aldoxorubicin + Bendamustine + Bortezomib Aldoxorubicin Bendamustine Bortezomib 0 0
Atezolizumab + Bendamustine + Obinutuzumab Atezolizumab Bendamustine Obinutuzumab 0 1
Avelumab + Bendamustine + Rituximab Avelumab Bendamustine Rituximab 0 1
Bendamustine Bendamustine 0 9
Bendamustine + Bortezomib + Ofatumumab Bendamustine Bortezomib Ofatumumab 0 1
Bendamustine + Bortezomib + Pegylated liposomal-doxorubicin Bendamustine Bortezomib Pegylated liposomal-doxorubicin 0 1
Bendamustine + Bortezomib + Rituximab Bendamustine Bortezomib Rituximab 1 0
Bendamustine + Brentuximab vedotin Bendamustine Brentuximab vedotin 0 2
Bendamustine + Brentuximab vedotin + Rituximab Bendamustine Brentuximab vedotin Rituximab 0 1
Bendamustine + CAR.k.28 cells + Fludarabine Bendamustine CAR.k.28 cells Fludarabine 0 1
Bendamustine + Copanlisib + Rituximab Bendamustine Copanlisib Rituximab 0 1
Bendamustine + CPI-613 Bendamustine CPI-613 0 1
Bendamustine + CUDC-907 + Rituximab Bendamustine CUDC-907 Rituximab 0 1
Bendamustine + Cytarabine + Etoposide Bendamustine Cytarabine Etoposide 0 1
Bendamustine + Cytarabine + Rituximab Bendamustine Cytarabine Rituximab 0 1
Bendamustine + Durvalumab + Rituximab Bendamustine Durvalumab Rituximab 0 1
Bendamustine + Everolimus Bendamustine Everolimus 0 1
Bendamustine + Fludarabine Bendamustine Fludarabine 0 1
Bendamustine + Fludarabine + iC9-CAR.19-IL15-Transduced CB-NK Bendamustine Fludarabine iC9-CAR.19-IL15-Transduced CB-NK 0 1
Bendamustine + Fludarabine + Inotuzumab ozogamicin Bendamustine Fludarabine Inotuzumab ozogamicin 0 1
Bendamustine + Fludarabine + Inotuzumab ozogamicin + Tacrolimus Bendamustine Fludarabine Inotuzumab ozogamicin Tacrolimus 0 1
Bendamustine + Fludarabine + Tisagenlecleucel Bendamustine Fludarabine Tisagenlecleucel 0 1
Bendamustine + Gemcitabine + Nivolumab Bendamustine Gemcitabine Nivolumab 0 1
Bendamustine + Idelalisib + Rituximab Bendamustine Idelalisib Rituximab 1 2
Bendamustine + Isatuximab + Prednisone Bendamustine Isatuximab Prednisone 0 1
Bendamustine + Mivavotinib Bendamustine Mivavotinib 0 1
Bendamustine + Mivavotinib + Rituximab Bendamustine Mivavotinib Rituximab 0 1
Bendamustine + MK2206 + Rituximab Bendamustine MK2206 Rituximab 1 0
Bendamustine + Obinutuzumab Bendamustine Obinutuzumab 1 2
Bendamustine + Obinutuzumab + Parsaclisib Bendamustine Obinutuzumab Parsaclisib 0 1
Bendamustine + Obinutuzumab + Venetoclax Bendamustine Obinutuzumab Venetoclax 1 3
Bendamustine + Ofatumumab Bendamustine Ofatumumab 0 1
Bendamustine + Olaparib Bendamustine Olaparib 1 0
Bendamustine + Otlertuzumab Bendamustine Otlertuzumab 0 1
Bendamustine + Parsaclisib + Rituximab Bendamustine Parsaclisib Rituximab 0 1
Bendamustine + Pembrolizumab Bendamustine Pembrolizumab 0 1
Bendamustine + PF-06747143 Bendamustine PF-06747143 0 0
Bendamustine + Polatuzumab vedotin-piiq + Rituximab Bendamustine Polatuzumab vedotin-piiq Rituximab 1 2
Bendamustine + Rituximab Bendamustine Rituximab 2 16
Bendamustine + Rituximab + Veliparib Bendamustine Rituximab Veliparib 2 0
Bendamustine + Rituximab + Venetoclax Bendamustine Rituximab Venetoclax 0 3
Bendamustine + Tafasitamab-cxix Bendamustine Tafasitamab-cxix 0 1
Bendamustine + Veliparib Bendamustine Veliparib 4 0


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