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|Drug Name||iC9-CAR.19-IL15-Transduced CB-NK|
|Synonyms||TAK 007|TAK-007|TAK 007|
iC9/CAR.19/IL15-Transduced CB-NK cells are cord blood-derived natural killer cells that have modified to express a chimeric antigen receptor directed to CD19, as well as IL-15 and inducible caspase-9, which may result in increased death of CD19-expressing tumor cells (PMID: 28725044).
|CAS Registry Number||NA|
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|
|Bendamustine + Fludarabine + iC9-CAR.19-IL15-Transduced CB-NK||Bendamustine Fludarabine iC9-CAR.19-IL15-Transduced CB-NK||0||1|
|Cyclophosphamide + Fludarabine + iC9-CAR.19-IL15-Transduced CB-NK||Cyclophosphamide Fludarabine iC9-CAR.19-IL15-Transduced CB-NK||0||1|
|iC9-CAR.19-IL15-Transduced CB-NK||iC9-CAR.19-IL15-Transduced CB-NK||0||2|