Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name Aldoxorubicin
Trade Name
Synonyms INNO-206|doxorubicin prodrug INNO-206
Drug Descriptions

Aldoxorubicin is a derivative prodrug of doxorubicin that is converted to free doxorubicin within the acidic environment within tumors. Once converted, doxorubicin intercalates DNA, inhibits DNA synthesis and induces apotosis (NCI Drug Dictionary).

DrugClasses Chemotherapy - Anthracycline 11

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Abexinostat + Aldoxorubicin Abexinostat Aldoxorubicin 1 0
Aldoxorubicin Aldoxorubicin 0 5
Aldoxorubicin + ALT-803 + Avelumab + Bevacizumab + Capecitabine + Cyclophosphamide + ETBX-011 + ETBX-021 + ETBX-051 + ETBX-061 + Fluorouracil + Gemcitabine + GI-4000 + GI-6207 + GI-6301 + haNK cells + Leucovorin + Nab-paclitaxel + Oxaliplatin ALT-803 Aldoxorubicin Avelumab Bevacizumab Capecitabine Cyclophosphamide ETBX-011 ETBX-021 ETBX-051 ETBX-061 Fluorouracil GI-4000 GI-6207 GI-6301 Gemcitabine Leucovorin Nab-paclitaxel Oxaliplatin haNK cells 0 2
Aldoxorubicin + ALT-803 + Avelumab + Capecitabine + Cetuximab + Cyclophosphamide + ETBX-011 + ETBX-021 + ETBX-051 + ETBX-061 + Fluorouracil + GI-4000 + GI-6207 + GI-6301 + haNK cells + Leucovorin + Nab-paclitaxel + Oxaliplatin + Regorafenib + Trastuzumab ALT-803 Aldoxorubicin Avelumab Capecitabine Cetuximab Cyclophosphamide ETBX-011 ETBX-021 ETBX-051 ETBX-061 Fluorouracil GI-4000 GI-6207 GI-6301 Leucovorin Nab-paclitaxel Oxaliplatin Regorafenib Trastuzumab haNK cells 0 1
Aldoxorubicin + ALT-803 + Avelumab + Capecitabine + Cetuximab + Cyclophosphamide + ETBX-011 + ETBX-051 + ETBX-061 + Fluorouracil + GI-4000 + GI-6207 + GI-6301 + haNK cells + Leucovorin + Nab-paclitaxel + Sorafenib ALT-803 Aldoxorubicin Avelumab Capecitabine Cetuximab Cyclophosphamide ETBX-011 ETBX-051 ETBX-061 Fluorouracil GI-4000 GI-6207 GI-6301 Leucovorin Nab-paclitaxel Sorafenib haNK cells 0 1
Aldoxorubicin + ALT-803 + Avelumab + Cetuximab + ETBX-051 + ETBX-061 + GI-6301 + haNK cells ALT-803 Aldoxorubicin Avelumab Cetuximab ETBX-051 ETBX-061 GI-6301 haNK cells 0 1
Aldoxorubicin + ALT-803 + Avelumab + Cisplatin + Cyclophosphamide + ETBX-011 + ETBX-051 + ETBX-061 + Fluorouracil + GI-4000 + GI-6301 + haNK cells + Paclitaxel ALT-803 Aldoxorubicin Avelumab Cisplatin Cyclophosphamide ETBX-011 ETBX-051 ETBX-061 Fluorouracil GI-4000 GI-6301 Paclitaxel haNK cells 0 1
Aldoxorubicin + ALT-803 + Avelumab + Cyclophosphamide + ETBX-011 + ETBX-051 + ETBX-061 + Fluorouracil + GI-4000 + GI-6207 + GI-6301 + haNK cells + Leucovorin + Nab-paclitaxel ALT-803 Aldoxorubicin Avelumab Cyclophosphamide ETBX-011 ETBX-051 ETBX-061 Fluorouracil GI-4000 GI-6207 GI-6301 Leucovorin Nab-paclitaxel haNK cells 0 1
Aldoxorubicin + Alvocidib Aldoxorubicin Alvocidib 1 0
Aldoxorubicin + B02 Aldoxorubicin B02 0 0
Aldoxorubicin + Bendamustine + Bortezomib Aldoxorubicin Bendamustine Bortezomib 0 0
Aldoxorubicin + BEZ235 Aldoxorubicin BEZ235 1 0
Aldoxorubicin + Buparlisib Aldoxorubicin Buparlisib 1 0
Aldoxorubicin + Cisplatin + Cyclophosphamide + Dexamethasone + Etoposide Aldoxorubicin Cisplatin Cyclophosphamide Dexamethasone Etoposide 0 1
Aldoxorubicin + Cisplatin + Filgrastim + Methotrexate + Vinblastine Aldoxorubicin Cisplatin Filgrastim Methotrexate Vinblastine 0 1
Aldoxorubicin + Cisplatin + Methotrexate + Vincristine Aldoxorubicin Cisplatin Methotrexate Vincristine 0 1
Aldoxorubicin + Cyclophosphamide + Prednisone + Rituximab + Vincristine Aldoxorubicin Cyclophosphamide Prednisone Rituximab Vincristine 0 1
Aldoxorubicin + Cyclophosphamide + Veliparib Aldoxorubicin Cyclophosphamide Veliparib 0 1
Aldoxorubicin + Docetaxel + Estramustine + Ketoconazole Aldoxorubicin Docetaxel Estramustine Ketoconazole 0 1
Aldoxorubicin + Durvalumab + Motolimod Aldoxorubicin Durvalumab Motolimod 0 1
Aldoxorubicin + Ganetespib Aldoxorubicin Ganetespib 0 1
Aldoxorubicin + Metformin Aldoxorubicin Metformin 1 0
Aldoxorubicin + Rigosertib Aldoxorubicin Rigosertib 1 0
Aldoxorubicin + Seliciclib Aldoxorubicin Seliciclib 0 0


Additional content available in CKB BOOST