Drug Detail


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Drug Name Seliciclib
Trade Name
Synonyms Roscovitine|CYC202
Drug Descriptions

Roscovotine (seliciclib) inhibits Cdc2, Cdk2 and Cdk5, which results in disruption of cell-cycle progression and decreased cell proliferation (PMID: 9030781, PMID: 9366565, PMID: 20822897)

DrugClasses CDK2 Inhibitor 30 CDK5 Inhibitor 8
CAS Registry Number 186692-46-6
NCIT ID C62783


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Aldoxorubicin + Seliciclib Aldoxorubicin Seliciclib 0 0
Alvocidib + Seliciclib Alvocidib Seliciclib 0 0
Doxorubicin + Seliciclib Doxorubicin Seliciclib 2 0
Sapacitabine + Seliciclib Sapacitabine Seliciclib 0 1
Seliciclib Seliciclib 8 0

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