Drug Detail

Drug Name Seliciclib
Trade Name Roscovitine
Synonyms CYC202
Drug Descriptions

Roscovotine (seliciclib) inhibits Cdc2, Cdk2 and Cdk5, which results in disruption of cell-cycle progression and decreased cell proliferation (PMID: 9030781, PMID: 9366565)

DrugClasses CDK2 Inhibitor 16 CDK5 Inhibitor 6

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Aldoxorubicin + Seliciclib Aldoxorubicin Seliciclib 0 0
Alvocidib + Seliciclib Alvocidib Seliciclib 0 0
Doxorubicin + Seliciclib Doxorubicin Seliciclib 2 0
sapacitabine + Seliciclib Seliciclib sapacitabine 0 1
Seliciclib Seliciclib 9 0


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