Drug Detail

Drug Name Doxorubicin
Trade Name Adriamycin
Synonyms Adria|ADR
Drug Descriptions

Adriamycin (doxorubicin) is an anthracycline chemotherapeutic, in a non-liposomal formulation, which intercalates into DNA and inhibits topoisomerase II (PMID: 24367159). Doxorubicin is FDA approved for multiple cancer types (FDA.gov).

DrugClasses Chemotherapy - Anthracycline 11 TOPO2 inhibitor 4

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Therapy Name Drugs Efficacy Evidence Clinical Trials
AB928 + Doxorubicin AB928 Doxorubicin 1 0
ABT-737 + Doxorubicin ABT-737 Doxorubicin 1 0
Acalabrutinib + Cyclophosphamide + Doxorubicin + Etoposide + Prednisone + Rituximab + Vincristine Acalabrutinib Cyclophosphamide Doxorubicin Etoposide Prednisone Rituximab Vincristine 0 1
Acalabrutinib + Cyclophosphamide + Doxorubicin + Prednisone + Rituximab + Vincristine Acalabrutinib Cyclophosphamide Doxorubicin Prednisone Rituximab Vincristine 0 1
ACY-957 + Doxorubicin ACY-957 Doxorubicin 1 0
Adavosertib + Doxorubicin Adavosertib Doxorubicin 0 0
Alectinib + Doxorubicin Alectinib Doxorubicin 1 0
Alvocidib + Doxorubicin Alvocidib Doxorubicin 1 0
AMG 232 + Doxorubicin AMG 232 Doxorubicin 0 0
Anastrozole + Cyclophosphamide + Doxorubicin + Paclitaxel + Pertuzumab + Trastuzumab Anastrozole Cyclophosphamide Doxorubicin Paclitaxel Pertuzumab Trastuzumab 0 0
Anastrozole + Cyclophosphamide + Doxorubicin + Paclitaxel + Trastuzumab Anastrozole Cyclophosphamide Doxorubicin Paclitaxel Trastuzumab 0 0
APR-246 + Carboplatin + Doxorubicin APR-246 Carboplatin Doxorubicin 0 1
APX005M + Doxorubicin + Olaratumab APX005M Doxorubicin Olaratumab 0 1
Atezolizumab + Cyclophosphamide + Doxorubicin Atezolizumab Cyclophosphamide Doxorubicin 0 1
AZD3463 + Doxorubicin AZD3463 Doxorubicin 1 0
Bevacizumab + Cyclophosphamide + Doxorubicin + Etoposide + Ifosfamide + Irinotecan + Sorafenib + Temozolomide + Temsirolimus + Vincristine Bevacizumab Cyclophosphamide Doxorubicin Etoposide Ifosfamide Irinotecan Sorafenib Temozolomide Temsirolimus Vincristine 0 1
Bevacizumab + Cyclophosphamide + Doxorubicin + Paclitaxel Bevacizumab Cyclophosphamide Doxorubicin Paclitaxel 0 1
Bevacizumab + Docetaxel + Doxorubicin Bevacizumab Docetaxel Doxorubicin 1 0
Bevacizumab + Doxorubicin Bevacizumab Doxorubicin 0 1
Bevacizumab + Doxorubicin + Durvalumab Bevacizumab Doxorubicin Durvalumab 0 1
Bevacizumab + Doxorubicin + Everolimus Bevacizumab Doxorubicin Everolimus 1 0
Bevacizumab + Doxorubicin + Temsirolimus Bevacizumab Doxorubicin Temsirolimus 1 1
Bleomycin + Dacarbazine + Doxorubicin + Nivolumab + Vinblastine Bleomycin Dacarbazine Doxorubicin Nivolumab Vinblastine 0 1
Bleomycin + Dacarbazine + Doxorubicin + Pembrolizumab + Vinblastine Bleomycin Dacarbazine Doxorubicin Pembrolizumab Vinblastine 0 1
Bleomycin + Dacarbazine + Doxorubicin + Vinblastine Bleomycin Dacarbazine Doxorubicin Vinblastine 0 1
Bortezomib + Dasatinib + Dexamethasone + Doxorubicin + Palbociclib Bortezomib Dasatinib Dexamethasone Doxorubicin Palbociclib 0 1
Brentuximab vedotin + Cyclophosphamide + Doxorubicin + Prednisone Brentuximab vedotin Cyclophosphamide Doxorubicin Prednisone 0 0
Brentuximab vedotin + Cyclophosphamide + Doxorubicin + Prednisone + Rituximab Brentuximab vedotin Cyclophosphamide Doxorubicin Prednisone Rituximab 0 1
Brentuximab vedotin + Dacarbazine + Doxorubicin + Nivolumab + Vinblastine Brentuximab vedotin Dacarbazine Doxorubicin Nivolumab Vinblastine 0 1
Brentuximab vedotin + Dacarbazine + Doxorubicin + Vinblastine Brentuximab vedotin Dacarbazine Doxorubicin Vinblastine 1 1
BTCT4465A + Cyclophosphamide + Doxorubicin + Polatuzumab Vedotin + Prednisone BTCT4465A Cyclophosphamide Doxorubicin Polatuzumab vedotin-piiq Prednisone 0 1
BTCT4465A + Cyclophosphamide + Doxorubicin + Prednisone + Vincristine BTCT4465A Cyclophosphamide Doxorubicin Prednisone Vincristine 0 1
Cambinol + Doxorubicin Cambinol Doxorubicin 1 0
Carboplatin + Cisplatin + Doxorubicin Carboplatin Cisplatin Doxorubicin 0 1
Carboplatin + Cisplatin + Doxorubicin + Etoposide Carboplatin Cisplatin Doxorubicin Etoposide 0 1
Carboplatin + Cisplatin + Doxorubicin + Irinotecan + Vincristine Carboplatin Cisplatin Doxorubicin Irinotecan Vincristine 0 1
Carboplatin + Cyclophosphamide + Doxorubicin + Paclitaxel Carboplatin Cyclophosphamide Doxorubicin Paclitaxel 0 1
Carboplatin + Doxorubicin Carboplatin Doxorubicin 0 1
Carboplatin + Doxorubicin + Etoposide Carboplatin Doxorubicin Etoposide 0 0
Carboplatin + Doxorubicin + Iniparib Carboplatin Doxorubicin Iniparib 0 1
Carboplatin + Doxorubicin + Irinotecan + Vincristine Carboplatin Doxorubicin Irinotecan Vincristine 0 0
Cisplatin + Cyclophosphamide + Doxorubicin Cisplatin Cyclophosphamide Doxorubicin 0 1
Cisplatin + Cyclophosphamide + Doxorubicin + Etoposide Cisplatin Cyclophosphamide Doxorubicin Etoposide 0 1
Cisplatin + Doxorubicin Cisplatin Doxorubicin 0 1
Cisplatin + Doxorubicin + Durvalumab + Methotrexate + Vinblastine Cisplatin Doxorubicin Durvalumab Methotrexate Vinblastine 0 1
Cisplatin + Doxorubicin + Fluorouracil + Vincristine Cisplatin Doxorubicin Fluorouracil Vincristine 0 1
Cisplatin + Doxorubicin + Gemcitabine + Oxaliplatin + Sorafenib Cisplatin Doxorubicin Gemcitabine Oxaliplatin Sorafenib 0 1
Cisplatin + Doxorubicin + Sorafenib Cisplatin Doxorubicin Sorafenib 0 1
CPI-0610 + Doxorubicin CPI-0610 Doxorubicin 1 0
Cyclophosphamide + Cytarabine + Dexamethasone + Doxorubicin + Leucovorin + Methotrexate + Pegaspargase + Thioguanine + Vincristine Cyclophosphamide Cytarabine Dexamethasone Doxorubicin Leucovorin Methotrexate Pegaspargase Thioguanine Vincristine 0 1
Cyclophosphamide + Cytarabine + Dexamethasone + Doxorubicin + Leucovorin + Methotrexate + Pegaspargase + Vincristine Cyclophosphamide Cytarabine Dexamethasone Doxorubicin Leucovorin Methotrexate Pegaspargase Vincristine 0 0
Cyclophosphamide + Cytarabine + Dexamethasone + Doxorubicin + Methotrexate + Pegaspargase + Thioguanine + Vincristine Cyclophosphamide Cytarabine Dexamethasone Doxorubicin Methotrexate Pegaspargase Thioguanine Vincristine 0 1
Cyclophosphamide + Cytarabine + Doxorubicin + Etoposide + Filgrastim + Ifosfamide + Leucovorin + Mesna + Methotrexate + Rituximab + Vincristine Cyclophosphamide Cytarabine Doxorubicin Etoposide Filgrastim Ifosfamide Leucovorin Mesna Methotrexate Rituximab Vincristine 0 1
Cyclophosphamide + Dexamethasone + Doxorubicin + Nelarabine + Pegaspargase + Venetoclax + Vincristine Cyclophosphamide Dexamethasone Doxorubicin Nelarabine Pegaspargase Venetoclax Vincristine 0 1
Cyclophosphamide + Dexamethasone + Doxorubicin + Rituximab + Vincristine Cyclophosphamide Dexamethasone Doxorubicin Rituximab Vincristine 0 1
Cyclophosphamide + Dexamethasone + Doxorubicin + Vincristine Cyclophosphamide Dexamethasone Doxorubicin Vincristine 0 2
Cyclophosphamide + Docetaxel + Doxorubicin Cyclophosphamide Docetaxel Doxorubicin 0 1
Cyclophosphamide + Doxorubicin Cyclophosphamide Doxorubicin 0 12
Cyclophosphamide + Doxorubicin + Durvalumab + Lenalidomide + Prednisone + Rituximab + Vincristine Cyclophosphamide Doxorubicin Durvalumab Lenalidomide Prednisone Rituximab Vincristine 0 1
Cyclophosphamide + Doxorubicin + Durvalumab + Prednisone + Rituximab + Vincristine Cyclophosphamide Doxorubicin Durvalumab Prednisone Rituximab Vincristine 0 1
Cyclophosphamide + Doxorubicin + Elenagen Cyclophosphamide Doxorubicin Elenagen 1 0
Cyclophosphamide + Doxorubicin + Eribulin Cyclophosphamide Doxorubicin Eribulin 0 1
Cyclophosphamide + Doxorubicin + Etoposide + Filgrastim + Ibrutinib + Pegfilgrastim + Prednisone + Rituximab + Vincristine Cyclophosphamide Doxorubicin Etoposide Filgrastim Ibrutinib Pegfilgrastim Prednisone Rituximab Vincristine 0 1
Cyclophosphamide + Doxorubicin + Etoposide + Fludarabine + Prednisone + Rituximab + Vincristine Cyclophosphamide Doxorubicin Etoposide Fludarabine Prednisone Rituximab Vincristine 0 1
Cyclophosphamide + Doxorubicin + Etoposide + Fludarabine + Prednisone + Vincristine Cyclophosphamide Doxorubicin Etoposide Fludarabine Prednisone Vincristine 0 1
Cyclophosphamide + Doxorubicin + Etoposide + Ifosfamide + Vincristine Cyclophosphamide Doxorubicin Etoposide Ifosfamide Vincristine 0 2
Cyclophosphamide + Doxorubicin + Etoposide + inotuzumab ozogamicin + Prednisone + Rituximab + Vincristine Cyclophosphamide Doxorubicin Etoposide Prednisone Rituximab Vincristine inotuzumab ozogamicin 0 1
Cyclophosphamide + Doxorubicin + Etoposide + inotuzumab ozogamicin + Prednisone + Vincristine Cyclophosphamide Doxorubicin Etoposide Prednisone Vincristine inotuzumab ozogamicin 0 1
Cyclophosphamide + Doxorubicin + Etoposide + Methylprednisolone + Rituximab + Vincristine Cyclophosphamide Doxorubicin Etoposide Methylprednisolone Rituximab Vincristine 0 4
Cyclophosphamide + Doxorubicin + Etoposide + Nivolumab + Prednisone + Rituximab + Vincristine Cyclophosphamide Doxorubicin Etoposide Nivolumab Prednisone Rituximab Vincristine 0 1
Cyclophosphamide + Doxorubicin + Etoposide + Nivolumab + Prednisone + Vincristine Cyclophosphamide Doxorubicin Etoposide Nivolumab Prednisone Vincristine 0 1
Cyclophosphamide + Doxorubicin + Etoposide + Pembrolizumab + Prednisone + Vincristine Cyclophosphamide Doxorubicin Etoposide Pembrolizumab Prednisone Vincristine 0 1
Cyclophosphamide + Doxorubicin + Etoposide + Prednisone + Rituximab + Venetoclax + Vincristine Cyclophosphamide Doxorubicin Etoposide Prednisone Rituximab Venetoclax Vincristine 0 1
Cyclophosphamide + Doxorubicin + Etoposide + Prednisone + Rituximab + Vincristine Cyclophosphamide Doxorubicin Etoposide Prednisone Rituximab Vincristine 0 1
Cyclophosphamide + Doxorubicin + Etoposide + Prednisone + Vincristine Cyclophosphamide Doxorubicin Etoposide Prednisone Vincristine 0 1
Cyclophosphamide + Doxorubicin + Etoposide + Vincristine Cyclophosphamide Doxorubicin Etoposide Vincristine 0 2
Cyclophosphamide + Doxorubicin + Exemestane + Paclitaxel + Pertuzumab + Trastuzumab Cyclophosphamide Doxorubicin Exemestane Paclitaxel Pertuzumab Trastuzumab 0 0
Cyclophosphamide + Doxorubicin + Exemestane + Paclitaxel + Trastuzumab Cyclophosphamide Doxorubicin Exemestane Paclitaxel Trastuzumab 0 0
Cyclophosphamide + Doxorubicin + Fluorouracil Cyclophosphamide Doxorubicin Fluorouracil 1 0
Cyclophosphamide + Doxorubicin + Letrozole + Paclitaxel + Pertuzumab + Trastuzumab Cyclophosphamide Doxorubicin Letrozole Paclitaxel Pertuzumab Trastuzumab 0 0
Cyclophosphamide + Doxorubicin + Letrozole + Paclitaxel + Trastuzumab Cyclophosphamide Doxorubicin Letrozole Paclitaxel Trastuzumab 0 0
Cyclophosphamide + Doxorubicin + MCS110 + Paclitaxel Cyclophosphamide Doxorubicin MCS110 Paclitaxel 0 1
Cyclophosphamide + Doxorubicin + Neratinib + Paclitaxel Cyclophosphamide Doxorubicin Neratinib Paclitaxel 0 2
Cyclophosphamide + Doxorubicin + Neratinib + Paclitaxel + Trastuzumab Cyclophosphamide Doxorubicin Neratinib Paclitaxel Trastuzumab 0 1
Cyclophosphamide + Doxorubicin + Nivolumab + Prednisone + Rituximab + Vincristine Cyclophosphamide Doxorubicin Nivolumab Prednisone Rituximab Vincristine 0 1
Cyclophosphamide + Doxorubicin + Obinutuzumab + Prednisone + RO7082859 + Vincristine Cyclophosphamide Doxorubicin Obinutuzumab Prednisone RO7082859 Vincristine 0 1
Cyclophosphamide + Doxorubicin + Obinutuzumab + Prednisone + Vincristine Cyclophosphamide Doxorubicin Obinutuzumab Prednisone Vincristine 1 2
Cyclophosphamide + Doxorubicin + Paclitaxel Cyclophosphamide Doxorubicin Paclitaxel 0 8
Cyclophosphamide + Doxorubicin + Paclitaxel + Pembrolizumab Cyclophosphamide Doxorubicin Paclitaxel Pembrolizumab 0 1
Cyclophosphamide + Doxorubicin + Paclitaxel + Pertuzumab + Tamoxifen + Trastuzumab Cyclophosphamide Doxorubicin Paclitaxel Pertuzumab Tamoxifen Trastuzumab 0 0
Cyclophosphamide + Doxorubicin + Paclitaxel + Pertuzumab + Trastuzumab Cyclophosphamide Doxorubicin Paclitaxel Pertuzumab Trastuzumab 1 2
Cyclophosphamide + Doxorubicin + Paclitaxel + Ruxolitinib Cyclophosphamide Doxorubicin Paclitaxel Ruxolitinib 0 1
Cyclophosphamide + Doxorubicin + Paclitaxel + Tamoxifen + Trastuzumab Cyclophosphamide Doxorubicin Paclitaxel Tamoxifen Trastuzumab 0 0
Cyclophosphamide + Doxorubicin + Paclitaxel + Trastuzumab Cyclophosphamide Doxorubicin Paclitaxel Trastuzumab 1 2
Cyclophosphamide + Doxorubicin + Pembrolizumab Cyclophosphamide Doxorubicin Pembrolizumab 0 0
Cyclophosphamide + Doxorubicin + Pembrolizumab + Prednisone + Rituximab + Vincristine Cyclophosphamide Doxorubicin Pembrolizumab Prednisone Rituximab Vincristine 0 1
Cyclophosphamide + Doxorubicin + Pertuzumab + Tamoxifen + Trastuzumab Cyclophosphamide Doxorubicin Pertuzumab Tamoxifen Trastuzumab 0 0
Cyclophosphamide + Doxorubicin + Polatuzumab Vedotin + Prednisone + Rituximab Cyclophosphamide Doxorubicin Polatuzumab vedotin-piiq Prednisone Rituximab 0 1
Cyclophosphamide + Doxorubicin + Prednisone Cyclophosphamide Doxorubicin Prednisone 0 1
Cyclophosphamide + Doxorubicin + Prednisone + Rituximab Cyclophosphamide Doxorubicin Prednisone Rituximab 0 1
Cyclophosphamide + Doxorubicin + Prednisone + Rituximab + RO7082859 + Vincristine Cyclophosphamide Doxorubicin Prednisone RO7082859 Rituximab Vincristine 0 1
Cyclophosphamide + Doxorubicin + Prednisone + Rituximab + TAK-659 + Vincristine Cyclophosphamide Doxorubicin Prednisone Rituximab TAK-659 Vincristine 0 1
Cyclophosphamide + Doxorubicin + Prednisone + Rituximab + Vincristine Cyclophosphamide Doxorubicin Prednisone Rituximab Vincristine 0 9
Cyclophosphamide + Doxorubicin + Prednisone + Vincristine Cyclophosphamide Doxorubicin Prednisone Vincristine 0 6
Cyclophosphamide + Doxorubicin + Vincristine Cyclophosphamide Doxorubicin Vincristine 0 3
Cytarabine + Doxorubicin + Methotrexate + Vincristine Cytarabine Doxorubicin Methotrexate Vincristine 0 1
Cytarabine + Doxorubicin + Palbociclib + Pegaspargase + Prednisolone + Vincristine Cytarabine Doxorubicin Palbociclib Pegaspargase Prednisolone Vincristine 0 1
Cytarabine + Doxorubicin + Palbociclib + Pegaspargase + Prednisone + Vincristine Cytarabine Doxorubicin Palbociclib Pegaspargase Prednisone Vincristine 0 1
Dacarbazine + Doxorubicin + Nivolumab + Vinblastine Dacarbazine Doxorubicin Nivolumab Vinblastine 0 1
Dacarbazine + Doxorubicin + Pembrolizumab + Vinblastine Dacarbazine Doxorubicin Pembrolizumab Vinblastine 0 2
Dactinomycin + Doxorubicin + Etoposide + Ifosfamide + Vincristine Dactinomycin Doxorubicin Etoposide Ifosfamide Vincristine 0 1
Dalantercept + Doxorubicin Dalantercept Doxorubicin 1 0
Dexamethasone + Doxorubicin Dexamethasone Doxorubicin 0 2
Dexamethasone + Doxorubicin + Methotrexate + Pegaspargase + Vincristine Dexamethasone Doxorubicin Methotrexate Pegaspargase Vincristine 0 1
Dexamethasone + Doxorubicin + MLN4924 + Pegaspargase + Vincristine Dexamethasone Doxorubicin MLN4924 Pegaspargase Vincristine 0 1
Dexamethasone + Doxorubicin + Pegaspargase + Vincristine Dexamethasone Doxorubicin Pegaspargase Vincristine 0 2
Dexamethasone + Doxorubicin + Vincristine Dexamethasone Doxorubicin Vincristine 0 1
Dinaciclib + Doxorubicin Dinaciclib Doxorubicin 1 0
Docetaxel + Doxorubicin + Pembrolizumab Docetaxel Doxorubicin Pembrolizumab 0 1
Doxorubicin Doxorubicin 2 44
Doxorubicin + Etoposide + Fludarabine + Vincristine Doxorubicin Etoposide Fludarabine Vincristine 0 1
Doxorubicin + Etoposide + Vincristine Doxorubicin Etoposide Vincristine 0 1
Doxorubicin + FX1 Doxorubicin FX1 0 0
Doxorubicin + GANT61 Doxorubicin GANT61 1 0
Doxorubicin + Gemcitabine + Pembrolizumab + Vinorelbine Doxorubicin Gemcitabine Pembrolizumab Vinorelbine 0 1
Doxorubicin + GSK2830371 Doxorubicin GSK2830371 1 0
Doxorubicin + I-CBP112 Doxorubicin I-CBP112 2 0
Doxorubicin + Ifosfamide Doxorubicin Ifosfamide 1 2
Doxorubicin + Ifosfamide + Mesna + Olaratumab Doxorubicin Ifosfamide Mesna Olaratumab 0 1
Doxorubicin + Ifosfamide + Pazopanib Doxorubicin Ifosfamide Pazopanib 0 1
Doxorubicin + Lurbinectedin Doxorubicin Lurbinectedin 1 0
Doxorubicin + MEDI5117 Doxorubicin MEDI5117 0 0
Doxorubicin + Nilotinib Doxorubicin Nilotinib 4 0
Doxorubicin + NU6027 Doxorubicin NU6027 1 0
Doxorubicin + NU7441 Doxorubicin NU7441 1 0
Doxorubicin + Olaratumab Doxorubicin Olaratumab 1 2
Doxorubicin + Olaratumab + Trabectedin Doxorubicin Olaratumab Trabectedin 0 1
Doxorubicin + OTS193320 Doxorubicin OTS193320 0 0
Doxorubicin + Paclitaxel Doxorubicin Paclitaxel 0 0
Doxorubicin + Pembrolizumab Doxorubicin Pembrolizumab 0 3
Doxorubicin + PLX4720 Doxorubicin PLX4720 1 0
Doxorubicin + Prexasertib Doxorubicin Prexasertib 1 0
Doxorubicin + RG7386 Doxorubicin RG7386 0 0
Doxorubicin + Ribociclib Doxorubicin Ribociclib 0 1
Doxorubicin + Safingol Doxorubicin Safingol 1 0
Doxorubicin + Seliciclib Doxorubicin Seliciclib 2 0
Doxorubicin + Selinexor Doxorubicin Selinexor 1 1
Doxorubicin + Sirolimus Doxorubicin Sirolimus 1 0
Doxorubicin + SLCB050 Doxorubicin SLCB050 1 0
Doxorubicin + Sorafenib Doxorubicin Sorafenib 0 1
Doxorubicin + SPI-001 Doxorubicin SPI-001 0 0
Doxorubicin + Tozasertib Doxorubicin Tozasertib 1 0
Doxorubicin + Trabectedin Doxorubicin Trabectedin 1 0
Doxorubicin + Vorinostat Doxorubicin Vorinostat 1 0


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