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Drug Name AZD3463
Trade Name
Synonyms AZD-3463|AZD 3463
Drug Descriptions

AZD3463 inhibits IGF1R and ALK, including wild-type and mutant ALK, and has additional activity against ROS1 fusions, which decreases downstream signaling resulting in reduced tumor cell growth (PMID: 26786851, PMID: 26372962, PMID: 32698744, PMID: 32355780).

DrugClasses ALK Inhibitor 23 IGF-1R Inhibitor 17 ROS1 Inhibitor 14
CAS Registry Number 1356962-20-3
NCIT ID NA

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Therapy Name Drugs Efficacy Evidence Clinical Trials
AZD3463 AZD3463 7 0
AZD3463 + Doxorubicin AZD3463 Doxorubicin 1 0


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