Drug Detail


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Drug Name ABT-737
Trade Name
Synonyms ABT737|ABT 737
Drug Descriptions

ABT-737 is a BH3 mimetic, which targets Bcl2, Bcl-xl, and Bcl-w to induce apoptosis (PMID: 32623836).

DrugClasses BCL-XL inhibitor 14 BCL2 inhibitor 27
CAS Registry Number 852808-04-9
NCIT ID C114384


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Therapy Name Drugs Efficacy Evidence Clinical Trials
ABT-737 ABT-737 0 0
ABT-737 + Anti-CD19 CAR-T cells ABT-737 Anti-CD19 CAR-T cells 0 0
ABT-737 + Azacitidine ABT-737 Azacitidine 0 0
ABT-737 + AZD4547 ABT-737 AZD4547 3 0
ABT-737 + AZD8055 + Trametinib ABT-737 AZD8055 Trametinib 0 0
ABT-737 + Cisplatin ABT-737 Cisplatin 0 0
ABT-737 + CYC065 ABT-737 CYC065 0 0
ABT-737 + Dactolisib ABT-737 Dactolisib 1 0
ABT-737 + Dactolisib + Trametinib ABT-737 Dactolisib Trametinib 0 0
ABT-737 + Doxorubicin ABT-737 Doxorubicin 0 0
ABT-737 + Gemcitabine ABT-737 Gemcitabine 0 0
ABT-737 + Infigratinib ABT-737 Infigratinib 3 0
ABT-737 + MK2206 + Trametinib ABT-737 MK2206 Trametinib 0 0
ABT-737 + Oxaliplatin ABT-737 Oxaliplatin 0 0
ABT-737 + PD173074 ABT-737 PD173074 3 0
ABT-737 + Perifosine ABT-737 Perifosine 0 0
ABT-737 + S63845 ABT-737 S63845 0 0
ABT-737 + Sapanisertib ABT-737 Sapanisertib 1 0
ABT-737 + Vorinostat ABT-737 Vorinostat 0 0

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