Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name ABT-737
Trade Name
Synonyms ABT737|ABT 737
Drug Descriptions

ABT-737 is a BH3 mimetic, which targets Bcl2, Bcl-xl, and Bcl-w to induce apoptosis (PMID: 32623836).

DrugClasses BCL-XL inhibitor 11 BCL2 inhibitor 17

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
ABT-737 ABT-737 1 0
ABT-737 + Anti-CD19 CAR T cells ABT-737 Anti-CD19 CAR T cells 0 0
ABT-737 + AZD4547 ABT-737 AZD4547 0 0
ABT-737 + AZD8055 + Trametinib ABT-737 AZD8055 Trametinib 1 0
ABT-737 + Cisplatin ABT-737 Cisplatin 1 0
ABT-737 + Dactolisib ABT-737 Dactolisib 0 0
ABT-737 + Dactolisib + Trametinib ABT-737 Dactolisib Trametinib 1 0
ABT-737 + Doxorubicin ABT-737 Doxorubicin 1 0
ABT-737 + Gemcitabine ABT-737 Gemcitabine 1 0
ABT-737 + Infigratinib ABT-737 Infigratinib 0 0
ABT-737 + MK2206 + Trametinib ABT-737 MK2206 Trametinib 1 0
ABT-737 + Oxaliplatin ABT-737 Oxaliplatin 0 0
ABT-737 + PD173074 ABT-737 PD173074 0 0
ABT-737 + Perifosine ABT-737 Perifosine 1 0
ABT-737 + Sapanisertib ABT-737 Sapanisertib 0 0
ABT-737 + Vorinostat ABT-737 Vorinostat 0 0


Additional content available in CKB BOOST