Drug Detail

Drug Name AZD4547
Trade Name
Synonyms
Drug Descriptions

AZD4547 selectively binds and inhibits FGFR1, 2, and 3, which may result in the inhibition of FGFR-mediated signal transduction pathways and inhibition of tumor cell proliferation (PMID: 22369928).

DrugClasses FGFR1 Inhibitor 21 FGFR2 Inhibitor 15 FGFR3 Inhibitor 12

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Therapy Name Drugs Efficacy Evidence Clinical Trials
AZD4547 AZD4547 71 3
AZD4547 + AZD8055 AZD4547 AZD8055 2 0
AZD4547 + Buparlisib AZD4547 Buparlisib 4 0
AZD4547 + Capivasertib AZD4547 Capivasertib 1 0
AZD4547 + Cisplatin + Gemcitabine AZD4547 Cisplatin Gemcitabine 1 0
AZD4547 + Crizotinib AZD4547 Crizotinib 1 0
AZD4547 + Durvalumab AZD4547 Durvalumab 0 1
AZD4547 + Gefitinib AZD4547 Gefitinib 2 0
AZD4547 + Lapatinib AZD4547 Lapatinib 1 0
AZD4547 + Sirolimus AZD4547 Sirolimus 2 0
AZD4547 + Trametinib AZD4547 Trametinib 0 0
AZD4547 + Vistusertib AZD4547 Vistusertib 3 0


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