Drug Detail

Drug Name Buparlisib
Trade Name
Synonyms BKM-120|BKM120
Drug Descriptions

Buparlisib (BKM120) specifically inhibits class I PI3K in the PI3K/AKT kinase (or protein kinase B) signaling pathway in an ATP-competitive manner, and may result in apoptotic activity and inhibition of cell proliferation (PMID: 22188813).

DrugClasses PI3K Inhibitor (Pan) 34

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Therapy Name Therapy Description
Encorafenib + BKM120
BKM120 + Bevacizumab
Buparlisib Buparlisib (BKM120) specifically inhibits class I PI3K in the PI3K/AKT kinase (or protein kinase B) signaling pathway in an ATP-competitive manner, and may result in apoptotic activity and inhibition of cell proliferation (PMID: 22188813).
BKM120 + Osimertinib
BKM120 + Capecitabine + Lapatinib
BKM120 + Trastuzumab
Buparlisib + Paclitaxel
BKM120 + Cetuximab
BKM120 + Trametinib
BKM120 + Lomustine
BKM120 + AG490
BKM120 + Navitoclax
BKM120 + BMS-777607
BKM120 + PU-H71
BKM120 + WEHI-539
BKM120 + Selumetinib
LEE011 + BKM120 + Letrozole
BKM120 + Cisplatin
BKM120 + Everolimus
BKM120 + Letrozole
BKM120 + Panobinostat
AZD4547 + BKM120
BKM120 + Trastuzumab + Pertuzumab
Fulvestrant + BKM120
Abiraterone + Buparlisib
BKM120 + Carboplatin
BKM120 + Gemcitabine + Cisplatin
BKM120 + Carboplatin + Paclitaxel
Binimetinib + BKM120
BKM120 + Crizotinib
BKM120 + LJM716
BKM120 + Capecitabine
BKM120 + Etoposide + Cisplatin
BKM120 + Ofatumumab
BKM120 + Doxorubicin
BKM120 + Abraxane
BKM120 + Vemurafenib
Buparlisib + Palbociclib
BKM120 + Trastuzumab + Lapatinib
BKM120 + Sonidegib
BKM120 + Fulvestrant + LEE011
BKM120 + Venetoclax
BKM120 + Panitumumab
BKM120 + Rituximab
BGJ398 + BKM120
BKM120 + Temozolomide
BKM120 + Pertuzumab
BKM120 + Erlotinib
LGX818 + MEK162 + BKM120
BKM120 + Olaparib
BKM120 + Capecitabine + Trastuzumab
Buparlisib + Ibrutinib
Abiraterone + BKM120 + Prednisone
BKM120 + INC280
A-1331852 + BKM120
BKM120 + BLZ945
BKM120 + Pemetrexed + Carboplatin
BKM120 + Docetaxel