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Drug Name E7046
Trade Name
Synonyms AN0025|E-7046|E 7046
Drug Descriptions

AN0025 (E7046) is a small molecule inhibitor of E2 receptor type 4 (EP4), which may result in antitumor activity including inhibition of cell proliferation and reduced tumor growth (Mol Cancer Ther 2015;14(12 Suppl 2):Abstract nr B198, PMID: 32554609).

DrugClasses

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Capecitabine + E7046 Capecitabine E7046 0 1
E7046 E7046 3 1
E7046 + Fluorouracil + Leucovorin + Oxaliplatin E7046 Fluorouracil Leucovorin Oxaliplatin 0 1
E7046 + Pembrolizumab E7046 Pembrolizumab 0 1
E7046 + Radiotherapy E7046 Radiotherapy 2 0


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