Drug Detail

Drug Name Letrozole
Trade Name Femara
Synonyms Letrozol
Drug Descriptions

Femara (letrozole) is an aromatase inhibitor, which inhibits estrogen synthesis (NCI Drug Dictionary). Femara (letrozole) is approved for postmenopausal women with hormone receptor positive breast cancer (FDA.gov).

DrugClasses Aromatase Inhibitor 3

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Abemaciclib + Anastrozole + Letrozole Abemaciclib Anastrozole Letrozole 0 1
Abemaciclib + Letrozole Abemaciclib Letrozole 0 1
Abemaciclib + Letrozole + LY3023414 Abemaciclib LY3023414 Letrozole 0 1
Abemaciclib + Letrozole + Xentuzumab Abemaciclib Letrozole Xentuzumab 0 1
Ado-trastuzumab emtansine + Letrozole + Palbociclib Ado-trastuzumab emtansine Letrozole Palbociclib 0 1
Alpelisib + Letrozole Alpelisib Letrozole 0 5
Alpelisib + Letrozole + Ribociclib Alpelisib Letrozole Ribociclib 0 1
Anastrozole + Letrozole Anastrozole Letrozole 0 1
Buparlisib + Letrozole Buparlisib Letrozole 0 1
Buparlisib + Letrozole + Ribociclib Buparlisib Letrozole Ribociclib 0 1
Carboplatin + Docetaxel + Letrozole + Pertuzumab + Trastuzumab Carboplatin Docetaxel Letrozole Pertuzumab Trastuzumab 0 0
Carboplatin + Docetaxel + Letrozole + Trastuzumab Carboplatin Docetaxel Letrozole Trastuzumab 0 0
Carotuximab + Everolimus + Letrozole Carotuximab Everolimus Letrozole 0 1
Copanlisib + Letrozole Copanlisib Letrozole 0 1
Copanlisib + Letrozole + Palbociclib Copanlisib Letrozole Palbociclib 0 1
Cyclophosphamide + Doxorubicin + Letrozole + Paclitaxel + Pertuzumab + Trastuzumab Cyclophosphamide Doxorubicin Letrozole Paclitaxel Pertuzumab Trastuzumab 0 0
Cyclophosphamide + Doxorubicin + Letrozole + Paclitaxel + Trastuzumab Cyclophosphamide Doxorubicin Letrozole Paclitaxel Trastuzumab 0 0
Durvalumab + Letrozole Durvalumab Letrozole 0 1
Everolimus + Letrozole Everolimus Letrozole 0 5
Everolimus + Letrozole + Metformin Everolimus Letrozole Metformin 1 0
Everolimus + Letrozole + Ribociclib Everolimus Letrozole Ribociclib 0 1
Everolimus + Letrozole + Trastuzumab Everolimus Letrozole Trastuzumab 0 1
Fulvestrant + Letrozole + Palbociclib Fulvestrant Letrozole Palbociclib 0 1
GDC-0077 + Letrozole GDC-0077 Letrozole 0 1
GDC-0077 + Letrozole + Palbociclib GDC-0077 Letrozole Palbociclib 0 1
Goserelin + Letrozole + Palbociclib Goserelin Letrozole Palbociclib 0 1
Goserelin + Letrozole + Ribociclib Goserelin Letrozole Ribociclib 0 1
Hydroxychloroquine + Letrozole + Palbociclib Hydroxychloroquine Letrozole Palbociclib 0 1
Imatinib + Letrozole Imatinib Letrozole 1 0
Lapatinib + Letrozole Lapatinib Letrozole 0 1
Lapatinib + Letrozole + Trastuzumab Lapatinib Letrozole Trastuzumab 0 0
Letrozole Letrozole 0 33
Letrozole + LY3023414 LY3023414 Letrozole 0 1
Letrozole + MCLA-128 Letrozole MCLA-128 0 1
Letrozole + Paclitaxel + Pegylated liposomal-doxorubicin + Tamoxifen Letrozole Paclitaxel Pegylated liposomal-doxorubicin Tamoxifen 0 1
Letrozole + Palbociclib Letrozole Palbociclib 0 4
Letrozole + Palbociclib + Pembrolizumab Letrozole Palbociclib Pembrolizumab 0 1
Letrozole + Palbociclib + PF-06952229 Letrozole PF-06952229 Palbociclib 0 1
Letrozole + Palbociclib + Trastuzumab Letrozole Palbociclib Trastuzumab 0 1
Letrozole + Palbociclib + Tucatinib Letrozole Palbociclib Tucatinib 0 1
Letrozole + Pembrolizumab Letrozole Pembrolizumab 0 1
Letrozole + Ribociclib Letrozole Ribociclib 1 7
Letrozole + Seribantumab Letrozole Seribantumab 0 0
Letrozole + Talimogene laherparepvec Letrozole Talimogene laherparepvec 0 1
Letrozole + Taselisib Letrozole Taselisib 0 0
Letrozole + Trastuzumab Letrozole Trastuzumab 0 0