Drug Detail

Drug Name LY3023414
Trade Name
Drug Descriptions

LY3023414 is an ATP competitive inhibitor of PI3K/mTOR, inhibits signaling of the PI3K/mTOR pathway, and has demonstrated antiproliferative activity against tumor cells (PMID: 24387334).

DrugClasses mTOR Inhibitor 50 PI3K Inhibitor (Pan) 34


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Abemaciclib + Fulvestrant + LY3023414 Abemaciclib Fulvestrant LY3023414 0 1
Abemaciclib + Letrozole + LY3023414 Abemaciclib LY3023414 Letrozole 0 1
Abemaciclib + LY3023414 Abemaciclib LY3023414 0 2
Letrozole + LY3023414 LY3023414 Letrozole 0 1
LY3023414 LY3023414 5 8
LY3023414 + LY3039478 LY3023414 LY3039478 0 1
LY3023414 + Midazolam LY3023414 Midazolam 0 1
LY3023414 + Prexasertib LY3023414 Prexasertib 0 1

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