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Drug Name Fulvestrant
Trade Name Faslodex
Synonyms ICI 182,780
Drug Descriptions

Faslodex (fulvestrant) is a competitive inhibitor of estrogen that binds and deforms estrogen receptors, and causes inhibition of growth in cultured estrogen-sensitive breast cancer cells and is FDA approved for use in patients with hormone receptor-positive breast cancer (FDA.gov).

DrugClasses Hormone - Anti-estrogens 25
CAS Registry Number 129453-61-8
NCIT ID C1379

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Therapy Name Drugs Efficacy Evidence Clinical Trials
177Lu-NeoB + Fulvestrant + Ribociclib 177Lu-NeoB Fulvestrant Ribociclib 0 1
Abemaciclib + Anastrozole + Fulvestrant Abemaciclib Anastrozole Fulvestrant 0 1
Abemaciclib + ARTS-021 + Fulvestrant ARTS-021 Abemaciclib Fulvestrant 0 0
Abemaciclib + Capivasertib + Fulvestrant Abemaciclib Capivasertib Fulvestrant 0 1
Abemaciclib + Copanlisib + Fulvestrant Abemaciclib Copanlisib Fulvestrant 0 1
Abemaciclib + Fulvestrant Abemaciclib Fulvestrant 0 16
Abemaciclib + Fulvestrant + Hydroxychloroquine Abemaciclib Fulvestrant Hydroxychloroquine 0 1
Abemaciclib + Fulvestrant + Letrozole Abemaciclib Fulvestrant Letrozole 0 1
Abemaciclib + Fulvestrant + LOXO-783 Abemaciclib Fulvestrant LOXO-783 0 1
Abemaciclib + Fulvestrant + Lucitanib Abemaciclib Fulvestrant Lucitanib 0 0
Abemaciclib + Fulvestrant + LY3023414 Abemaciclib Fulvestrant LY3023414 0 1
Abemaciclib + Fulvestrant + RLY-5836 Abemaciclib Fulvestrant RLY-5836 0 1
Abemaciclib + Fulvestrant + RO5126766 Abemaciclib Fulvestrant RO5126766 0 1
Abemaciclib + Fulvestrant + Trastuzumab Abemaciclib Fulvestrant Trastuzumab 0 1
Abemaciclib + Fulvestrant + Xentuzumab Abemaciclib Fulvestrant Xentuzumab 0 1
Abemaciclib + Fulvestrant + Zotatifin Abemaciclib Fulvestrant Zotatifin 0 1
Abexinostat + Fulvestrant + Palbociclib Abexinostat Fulvestrant Palbociclib 0 1
Afuresertib + Fulvestrant Afuresertib Fulvestrant 0 1
Alisertib + Fulvestrant Alisertib Fulvestrant 0 2
Alpelisib + Canagliflozin + Fulvestrant Alpelisib Canagliflozin Fulvestrant 0 1
Alpelisib + Dapagliflozin + Fulvestrant + Metformin Alpelisib Dapagliflozin Fulvestrant Metformin 0 1
Alpelisib + Fulvestrant Alpelisib Fulvestrant 0 12
Alpelisib + Fulvestrant + Lapatinib Alpelisib Fulvestrant Lapatinib 0 0
Alpelisib + Fulvestrant + Metformin Alpelisib Fulvestrant Metformin 0 2
Alpelisib + Fulvestrant + Ribociclib Alpelisib Fulvestrant Ribociclib 0 1
Alpelisib + Fulvestrant + SDX-7320 Alpelisib Fulvestrant SDX-7320 0 1
Alpelisib + Fulvestrant + Trastuzumab Alpelisib Fulvestrant Trastuzumab 0 1
Alpelisib + Fulvestrant + Tucatinib Alpelisib Fulvestrant Tucatinib 0 1
Alpelisib + Fulvestrant + Zoledronic acid Alpelisib Fulvestrant Zoledronic acid 0 0
Anastrozole + Everolimus + Fulvestrant Anastrozole Everolimus Fulvestrant 0 1
Anastrozole + Fulvestrant Anastrozole Fulvestrant 0 2
ARQ 751 + Fulvestrant ARQ 751 Fulvestrant 0 1
ARTS-021 + Fulvestrant + Palbociclib ARTS-021 Fulvestrant Palbociclib 0 1
ARTS-021 + Fulvestrant + Ribociclib ARTS-021 Fulvestrant Ribociclib 0 0
Atezolizumab + Bevacizumab + Fulvestrant Atezolizumab Bevacizumab Fulvestrant 0 1
Atezolizumab + Fulvestrant Atezolizumab Fulvestrant 0 1
Atezolizumab + Fulvestrant + Ipatasertib Atezolizumab Fulvestrant Ipatasertib 0 1
Avelumab + Fulvestrant + Palbociclib Avelumab Fulvestrant Palbociclib 0 1
AZD4547 + Fulvestrant AZD4547 Fulvestrant 1 0
AZD4573 + Fulvestrant + Palbociclib AZD4573 Fulvestrant Palbociclib 0 0
AZD8835 + Fulvestrant AZD8835 Fulvestrant 0 0
AZD8835 + Fulvestrant + Palbociclib AZD8835 Fulvestrant Palbociclib 0 0
BG-68501 + Fulvestrant BG-68501 Fulvestrant 0 1
BGB-43395 + Fulvestrant BGB-43395 Fulvestrant 0 1
Binimetinib + Fulvestrant Binimetinib Fulvestrant 0 2
Birinapant + Fulvestrant Birinapant Fulvestrant 0 0
BLU-222 + Fulvestrant BLU-222 Fulvestrant 0 1
BLU-222 + Fulvestrant + Ribociclib BLU-222 Fulvestrant Ribociclib 0 1
Bosutinib + Fulvestrant + Palbociclib Bosutinib Fulvestrant Palbociclib 0 1
Buparlisib + Fulvestrant Buparlisib Fulvestrant 0 2
Buparlisib + Fulvestrant + Ribociclib Buparlisib Fulvestrant Ribociclib 0 1
C188-9 + Fulvestrant C188-9 Fulvestrant 0 1
Cabozantinib + Fulvestrant Cabozantinib Fulvestrant 0 1
Capivasertib + Fulvestrant Capivasertib Fulvestrant 0 2
Capivasertib + Fulvestrant + Lapatinib Capivasertib Fulvestrant Lapatinib 0 0
Capivasertib + Fulvestrant + Palbociclib Capivasertib Fulvestrant Palbociclib 0 1
Capivasertib + Fulvestrant + Ribociclib Capivasertib Fulvestrant Ribociclib 0 1
Ceritinib + Fulvestrant Ceritinib Fulvestrant 1 0
CFI-402257 + Fulvestrant CFI-402257 Fulvestrant 0 1
Copanlisib + Fulvestrant Copanlisib Fulvestrant 0 2
Crizotinib + Fulvestrant Crizotinib Fulvestrant 0 1
Dalpiciclib + Fulvestrant Dalpiciclib Fulvestrant 0 0
Danusertib + Fulvestrant Danusertib Fulvestrant 0 0
Dasatinib + Fulvestrant Dasatinib Fulvestrant 0 0
Debio 1347 + Fulvestrant Debio 1347 Fulvestrant 0 1
Dovitinib + Fulvestrant Dovitinib Fulvestrant 0 1
Durvalumab + Fulvestrant + Olaparib Durvalumab Fulvestrant Olaparib 0 1
Elacestrant + Fulvestrant Elacestrant Fulvestrant 0 0
Enzalutamide + Fulvestrant Enzalutamide Fulvestrant 0 2
Erdafitinib + Fulvestrant + Palbociclib Erdafitinib Fulvestrant Palbociclib 0 1
Everolimus + Fulvestrant Everolimus Fulvestrant 0 6
Everolimus + Fulvestrant + Neratinib Everolimus Fulvestrant Neratinib 0 0
FIIN-2 + Fulvestrant FIIN-2 Fulvestrant 0 0
FIIN-3 + Fulvestrant FIIN-3 Fulvestrant 1 0
Fulvestrant Fulvestrant 2 68
Fulvestrant + Futibatinib Fulvestrant Futibatinib 0 1
Fulvestrant + G1T38 Fulvestrant G1T38 0 1
Fulvestrant + Gedatolisib Fulvestrant Gedatolisib 0 1
Fulvestrant + Gedatolisib + Palbociclib Fulvestrant Gedatolisib Palbociclib 0 1
Fulvestrant + GS-5829 Fulvestrant GS-5829 0 1
Fulvestrant + Inavolisib Fulvestrant Inavolisib 0 2
Fulvestrant + Inavolisib + Palbociclib Fulvestrant Inavolisib Palbociclib 0 1
Fulvestrant + Infigratinib + Palbociclib Fulvestrant Infigratinib Palbociclib 0 1
Fulvestrant + Ipatasertib Fulvestrant Ipatasertib 0 2
Fulvestrant + Ipatasertib + Lapatinib Fulvestrant Ipatasertib Lapatinib 0 0
Fulvestrant + Ipatasertib + Palbociclib Fulvestrant Ipatasertib Palbociclib 0 3
Fulvestrant + Ixazomib Fulvestrant Ixazomib 0 1
Fulvestrant + JNJ-7706621 Fulvestrant JNJ-7706621 0 0
Fulvestrant + Lapatinib Fulvestrant Lapatinib 0 0
Fulvestrant + Lapatinib + Sirolimus Fulvestrant Lapatinib Sirolimus 0 0
Fulvestrant + Larotrectinib Fulvestrant Larotrectinib 0 0
Fulvestrant + Lenvatinib + Pembrolizumab Fulvestrant Lenvatinib Pembrolizumab 0 1
Fulvestrant + Letrozole Fulvestrant Letrozole 0 0
Fulvestrant + Letrozole + Palbociclib Fulvestrant Letrozole Palbociclib 0 1
Fulvestrant + LOXO-783 Fulvestrant LOXO-783 0 1
Fulvestrant + Lucitanib Fulvestrant Lucitanib 0 0
Fulvestrant + Lucitanib + Palbociclib Fulvestrant Lucitanib Palbociclib 0 0
Fulvestrant + M1774 Fulvestrant M1774 0 1
Fulvestrant + MEN1611 + Trastuzumab Fulvestrant MEN1611 Trastuzumab 0 1
Fulvestrant + Milademetan Fulvestrant Milademetan 0 1
Fulvestrant + MK2206 Fulvestrant MK2206 0 0
Fulvestrant + MK2206 + Ribociclib Fulvestrant MK2206 Ribociclib 1 0
Fulvestrant + Molibresib Fulvestrant Molibresib 0 1
Fulvestrant + Neratinib Fulvestrant Neratinib 0 6
Fulvestrant + Neratinib + Trastuzumab Fulvestrant Neratinib Trastuzumab 0 2
Fulvestrant + Niraparib Fulvestrant Niraparib 0 1
Fulvestrant + NUV-422 Fulvestrant NUV-422 0 1
Fulvestrant + OKI-219 Fulvestrant OKI-219 0 1
Fulvestrant + Olaparib + Palbociclib Fulvestrant Olaparib Palbociclib 0 1
Fulvestrant + Onapristone Fulvestrant Onapristone 0 1
Fulvestrant + Palbociclib Fulvestrant Palbociclib 2 24
Fulvestrant + Palbociclib + PD173074 Fulvestrant PD173074 Palbociclib 0 0
Fulvestrant + Palbociclib + Pembrolizumab Fulvestrant Palbociclib Pembrolizumab 0 1
Fulvestrant + Palbociclib + PF-07248144 Fulvestrant PF-07248144 Palbociclib 0 1
Fulvestrant + Palbociclib + Pictilisib Fulvestrant Palbociclib Pictilisib 0 0
Fulvestrant + Palbociclib + RLY-5836 Fulvestrant Palbociclib RLY-5836 0 1
Fulvestrant + Palbociclib + Rogaratinib Fulvestrant Palbociclib Rogaratinib 0 1
Fulvestrant + Palbociclib + SHP099 Fulvestrant Palbociclib SHP099 0 0
Fulvestrant + Palbociclib + SHP099 + Trametinib Fulvestrant Palbociclib SHP099 Trametinib 0 0
Fulvestrant + Palbociclib + Taselisib Fulvestrant Palbociclib Taselisib 0 0
Fulvestrant + Palbociclib + Trametinib Fulvestrant Palbociclib Trametinib 0 0
Fulvestrant + Palbociclib + Trastuzumab Fulvestrant Palbociclib Trastuzumab 0 1
Fulvestrant + Palbociclib + Tucatinib Fulvestrant Palbociclib Tucatinib 0 0
Fulvestrant + Palbociclib + Vistusertib Fulvestrant Palbociclib Vistusertib 0 1
Fulvestrant + Palbociclib + Volasertib Fulvestrant Palbociclib Volasertib 0 0
Fulvestrant + Palbociclib + ZW25 Fulvestrant Palbociclib ZW25 0 1
Fulvestrant + PD-0325901 Fulvestrant PD-0325901 0 0
Fulvestrant + PD173074 Fulvestrant PD173074 0 0
Fulvestrant + Pembrolizumab Fulvestrant Pembrolizumab 0 1
Fulvestrant + Pertuzumab + Ribociclib + Trastuzumab Fulvestrant Pertuzumab Ribociclib Trastuzumab 0 1
Fulvestrant + Pertuzumab + Trastuzumab Fulvestrant Pertuzumab Trastuzumab 0 0
Fulvestrant + Pertuzumab + Trastuzumab + Tucatinib Fulvestrant Pertuzumab Trastuzumab Tucatinib 0 1
Fulvestrant + PF-06873600 Fulvestrant PF-06873600 0 0
Fulvestrant + PF-07104091 + PF-07220060 Fulvestrant PF-07104091 PF-07220060 0 1
Fulvestrant + PF-07220060 Fulvestrant PF-07220060 0 2
Fulvestrant + PF-07248144 Fulvestrant PF-07248144 0 1
Fulvestrant + Pictilisib Fulvestrant Pictilisib 2 0
Fulvestrant + Poziotinib Fulvestrant Poziotinib 0 0
Fulvestrant + REGN2878-DM1 Fulvestrant REGN2878-DM1 0 0
Fulvestrant + Regorafenib Fulvestrant Regorafenib 0 1
Fulvestrant + Repotrectinib Fulvestrant Repotrectinib 0 0
Fulvestrant + Ribociclib Fulvestrant Ribociclib 1 13
Fulvestrant + Ribociclib + RLY-2608 Fulvestrant RLY-2608 Ribociclib 0 0
Fulvestrant + Ribociclib + RLY-5836 Fulvestrant RLY-5836 Ribociclib 0 1
Fulvestrant + Ribociclib + Spartalizumab Fulvestrant Ribociclib Spartalizumab 0 1
Fulvestrant + Ribociclib + Trastuzumab + Tucatinib Fulvestrant Ribociclib Trastuzumab Tucatinib 0 1
Fulvestrant + RLY-2608 Fulvestrant RLY-2608 0 1
Fulvestrant + RLY-5836 Fulvestrant RLY-5836 0 1
Fulvestrant + Samuraciclib Fulvestrant Samuraciclib 0 2
Fulvestrant + Sapanisertib Fulvestrant Sapanisertib 0 2
Fulvestrant + SAR405838 Fulvestrant SAR405838 0 0
Fulvestrant + Selumetinib Fulvestrant Selumetinib 0 0
Fulvestrant + Seribantumab Fulvestrant Seribantumab 0 1
Fulvestrant + SHP099 Fulvestrant SHP099 0 0
Fulvestrant + SHP099 + Trametinib Fulvestrant SHP099 Trametinib 0 0
Fulvestrant + STX-478 Fulvestrant STX-478 0 1
Fulvestrant + SY-1365 Fulvestrant SY-1365 0 1
Fulvestrant + SY-5609 Fulvestrant SY-5609 0 0
Fulvestrant + Talimogene laherparepvec Fulvestrant Talimogene laherparepvec 0 1
Fulvestrant + Taselisib Fulvestrant Taselisib 0 1
Fulvestrant + THZ1 Fulvestrant THZ1 0 0
Fulvestrant + Trametinib Fulvestrant Trametinib 0 0
Fulvestrant + Trastuzumab Fulvestrant Trastuzumab 0 0
Fulvestrant + Trastuzumab + Tucatinib Fulvestrant Trastuzumab Tucatinib 0 1
Fulvestrant + Trastuzumab + TVB-2640 Fulvestrant TVB-2640 Trastuzumab 0 1
Fulvestrant + Trastuzumab deruxtecan Fulvestrant Trastuzumab deruxtecan 0 1
Fulvestrant + Venetoclax Fulvestrant Venetoclax 0 1
Fulvestrant + Vistusertib Fulvestrant Vistusertib 0 1
Fulvestrant + VX-11e Fulvestrant VX-11e 0 0
Fulvestrant + XL102 Fulvestrant XL102 0 1
Fulvestrant + Zenocutuzumab Fulvestrant Zenocutuzumab 0 1
Fulvestrant + Zotatifin Fulvestrant Zotatifin 0 1


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