Drug Detail


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Drug Name ARQ 751
Trade Name
Synonyms ARQ-751|ARQ751
Drug Descriptions

ARQ 751 is an inhibitor of AKT1, AKT2, and AKT3, which may result in inhibition of the AKT/PI3K/MTOR pathway, thereby leading to tumor growth inhibition (PMID: 26469692).

DrugClasses Akt Inhibitor (Pan) 21
CAS Registry Number NA
NCIT ID C128250


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Therapy Name Drugs Efficacy Evidence Clinical Trials
ARQ 751 ARQ 751 11 1
ARQ 751 + AZD0156 ARQ 751 AZD0156 1 0
ARQ 751 + Fulvestrant ARQ 751 Fulvestrant 0 1
ARQ 751 + GSK2334470 ARQ 751 GSK2334470 1 0
ARQ 751 + KU-57788 ARQ 751 KU-57788 1 0
ARQ 751 + LAM-002A ARQ 751 LAM-002A 1 0
ARQ 751 + OSU-T315 ARQ 751 OSU-T315 1 0
ARQ 751 + Paclitaxel ARQ 751 Paclitaxel 0 1
ARQ 751 + Sirolimus ARQ 751 Sirolimus 1 0
ARQ 751 + Torin 1 ARQ 751 Torin 1 1 0

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