Drug Detail


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Drug Name GSK2334470
Trade Name
Synonyms GSK-470
Drug Descriptions

GSK2334470 is a small molecule inhibitor of PDPK1, which subsequently results in suppression of Akt and may result in antiproliferative activity (PMID: 29658600, PMID: 32188393).

DrugClasses PDPK1 Inhibitor 10
CAS Registry Number 1227911-45-6


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Alpelisib + GSK2334470 Alpelisib GSK2334470 1 0
ARQ 751 + GSK2334470 ARQ 751 GSK2334470 1 0
GSK2334470 GSK2334470 0 0
GSK2334470 + GSK690693 GSK2334470 GSK690693 1 0
GSK2334470 + Idelalisib GSK2334470 Idelalisib 1 0
GSK2334470 + Ipatasertib GSK2334470 Ipatasertib 1 0
GSK2334470 + Miransertib GSK2334470 Miransertib 2 0
GSK2334470 + MK2206 GSK2334470 MK2206 1 0
GSK2334470 + Osimertinib GSK2334470 Osimertinib 0 0
GSK2334470 + Palbociclib GSK2334470 Palbociclib 0 0
GSK2334470 + Trametinib GSK2334470 Trametinib 2 0

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