Drug Detail


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Drug Name Miransertib
Trade Name
Synonyms ARQ-092|ARQ092|ARQ 092
Drug Descriptions

Miransertib (ARQ092) is a pan-AKT inhibitor, resulting in inhibition of the PI3K/AKT signaling pathway and cell proliferation (PMID: 26469692, PMID: 31058421).

DrugClasses Akt Inhibitor (Pan) 21
CAS Registry Number 1313881-70-7
NCIT ID C99172


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Therapy Name Drugs Efficacy Evidence Clinical Trials
AZD0156 + Miransertib AZD0156 Miransertib 2 0
GSK2334470 + Miransertib GSK2334470 Miransertib 2 0
KU-57788 + Miransertib KU-57788 Miransertib 2 0
Miransertib Miransertib 22 2
Miransertib + OSU-T315 Miransertib OSU-T315 2 0
Miransertib + Paclitaxel Miransertib Paclitaxel 0 0
Miransertib + Sirolimus Miransertib Sirolimus 1 0
Miransertib + Torin 1 Miransertib Torin 1 1 0
Miransertib + Trametinib Miransertib Trametinib 1 0
Miransertib + Trastuzumab Miransertib Trastuzumab 0 0

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