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Drug Name GSK690693
Trade Name
Synonyms GSK-690693
Drug Descriptions

GSK690693 is a ATP-competitive pan-AKT inhibitor, which inhibits AKT signaling, resulting in decreased proliferation and increased apoptosis of tumor cells (PMID: 18381444, PMID: 31377021).

DrugClasses AKT Inhibitor (Pan) - ATP competitive 7
CAS Registry Number 937174-76-0
NCIT ID C71711

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Therapy Name Drugs Efficacy Evidence Clinical Trials
AZD0156 + GSK690693 AZD0156 GSK690693 1 0
Cisplatin + GSK690693 Cisplatin GSK690693 0 0
Fluorouracil + GSK690693 Fluorouracil GSK690693 0 0
GSK2334470 + GSK690693 GSK2334470 GSK690693 1 0
GSK690693 GSK690693 7 0
GSK690693 + HQP1351 GSK690693 HQP1351 0 0
GSK690693 + Imatinib GSK690693 Imatinib 0 0
GSK690693 + KU-57788 GSK690693 KU-57788 1 0
GSK690693 + LAM-003 GSK690693 LAM-003 0 0
GSK690693 + Lapatinib GSK690693 Lapatinib 0 0
GSK690693 + Nilotinib GSK690693 Nilotinib 0 0
GSK690693 + OSU-T315 GSK690693 OSU-T315 1 0
GSK690693 + Sirolimus GSK690693 Sirolimus 1 0
GSK690693 + Torin 1 GSK690693 Torin 1 1 0
GSK690693 + Venetoclax GSK690693 Venetoclax 1 0


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