Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : ckbsupport@jax.org
Drug Name | Lapatinib |
Trade Name | Tykerb |
Synonyms | Lapatinib Ditosylate |
Drug Descriptions |
Tykerb (lapatinib) reversibly inhibits ERBB2 (HER2) and EGFR, resulting in decreased downstream signaling and potentially leading to reduced tumor growth (PMID: 22477724). Tykerb (lapatinib) is FDA approved for ERBB2 (HER2)-positive (overexpressing) breast cancer (FDA.gov). |
DrugClasses | EGFR Inhibitor (Pan) 56 HER2 Inhibitor 38 |
CAS Registry Number | 388082-78-8 |
NCIT ID | C66878 |