Drug Detail


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Drug Name S63845
Trade Name
Synonyms MIK655|MIK-655|MIK 655|S-63845|S 63845
Drug Descriptions

S63845 (MIK655) is a small molecule drug that binds to and inhibits Mcl1, leading to apoptosis in tumor cells (PMID: 27760111, PMID: 32513939).

DrugClasses MCL1 Inhibitor 15
CAS Registry Number 1799633-27-4


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Capmatinib + S63845 Capmatinib S63845 0 0
Docetaxel + S63845 Docetaxel S63845 1 0
DT2216 + S63845 DT2216 S63845 1 0
Erlotinib + S63845 Erlotinib S63845 0 0
Lapatinib + S63845 Lapatinib S63845 0 0
S63845 S63845 4 0
S63845 + Trametinib S63845 Trametinib 2 0
S63845 + Trastuzumab S63845 Trastuzumab 0 0
S63845 + Vemurafenib S63845 Vemurafenib 1 0

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