Drug Detail

Drug Name Navitoclax
Trade Name
Synonyms ABT-263
Drug Descriptions

Navitoclax (ABT-263) is a BCL2, BCL-XL, and BCL-W inhibitor, which may enhance the efficacy of chemotherapeutics (PMID: 25787766).

DrugClasses BCL-XL inhibitor 9 BCL2 inhibitor 15

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Abiraterone + Navitoclax Abiraterone Navitoclax 0 1
Alpelisib + CGM097 + Navitoclax + Trametinib Alpelisib CGM097 Navitoclax Trametinib 0 0
Alpelisib + Dabrafenib + Erlotinib + Navitoclax Alpelisib Dabrafenib Erlotinib Navitoclax 1 0
Alpelisib + Erlotinib + Navitoclax + Trametinib Alpelisib Erlotinib Navitoclax Trametinib 0 0
Barasertib + Navitoclax Barasertib Navitoclax 3 0
BETd-246 + Navitoclax BETd-246 Navitoclax 1 0
Buparlisib + Navitoclax Buparlisib Navitoclax 0 0
Cabozantinib + Navitoclax Cabozantinib Navitoclax 1 0
CGM097 + Dabrafenib + Navitoclax + PF-04217903 CGM097 Dabrafenib Navitoclax PF-04217903 1 0
CGM097 + Navitoclax + Trametinib CGM097 Navitoclax Trametinib 0 0
Crizotinib + Navitoclax Crizotinib Navitoclax 1 0
Dabrafenib + Navitoclax + Trametinib Dabrafenib Navitoclax Trametinib 0 1
G-TPP + Navitoclax G-TPP Navitoclax 4 0
Gemcitabine + Navitoclax Gemcitabine Navitoclax 0 0
Ipatasertib + Navitoclax Ipatasertib Navitoclax 0 0
Navitoclax Navitoclax 1 0
Navitoclax + ONC201 Navitoclax ONC201 1 0
Navitoclax + Osimertinib Navitoclax Osimertinib 0 1
Navitoclax + Paclitaxel Navitoclax Paclitaxel 1 0
Navitoclax + Pictilisib Navitoclax Pictilisib 2 0
Navitoclax + PLX4720 Navitoclax PLX4720 1 0
Navitoclax + SCH772984 Navitoclax SCH772984 0 0
Navitoclax + Sorafenib Navitoclax Sorafenib 0 1
Navitoclax + TAK-901 Navitoclax TAK-901 3 0
Navitoclax + Trametinib Navitoclax Trametinib 3 1
Navitoclax + Vemurafenib Navitoclax Vemurafenib 3 0
Navitoclax + Venetoclax Navitoclax Venetoclax 0 1
Navitoclax + Vistusertib Navitoclax Vistusertib 0 1
Navitoclax + YM155 Navitoclax YM155 0 0


Additional content available in CKB BOOST