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Drug Name SCH772984
Trade Name
Synonyms SCH984|SCH-772984
Drug Descriptions

SCH772984 is an ATP-competitive inhibitor of both ERK1 and ERK2, which may result in growth inhibition and tumor regression (PMID: 23614898, PMID: 32371878).

DrugClasses ERK Inhibitor (pan) 21
CAS Registry Number 942183-80-4
NCIT ID NA

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Abemaciclib + SCH772984 Abemaciclib SCH772984 0 0
AZD8055 + SCH772984 AZD8055 SCH772984 0 0
AZD8186 + SCH772984 AZD8186 SCH772984 0 0
BMS-754807 + SCH772984 BMS-754807 SCH772984 0 0
Cetuximab + Dabrafenib + SCH772984 Cetuximab Dabrafenib SCH772984 2 0
Cetuximab + SCH772984 Cetuximab SCH772984 2 0
Dabrafenib + SCH772984 Dabrafenib SCH772984 3 0
Dabrafenib + SCH772984 + Trametinib Dabrafenib SCH772984 Trametinib 2 0
Danusertib + SCH772984 Danusertib SCH772984 0 0
Dasatinib + SCH772984 Dasatinib SCH772984 1 0
Everolimus + SCH772984 Everolimus SCH772984 0 0
G1T38 + SCH772984 G1T38 SCH772984 0 0
HRX-0233 + SCH772984 HRX-0233 SCH772984 0 0
Ipatasertib + SCH772984 Ipatasertib SCH772984 0 0
JQ1 + SCH772984 JQ1 SCH772984 0 0
Lapatinib + SCH772984 Lapatinib SCH772984 1 0
Lifirafenib + SCH772984 Lifirafenib SCH772984 3 0
Linsitinib + SCH772984 Linsitinib SCH772984 0 0
LY3214996 + SCH772984 LY3214996 SCH772984 0 0
Midostaurin + SCH772984 Midostaurin SCH772984 0 0
MK2206 + SCH772984 MK2206 SCH772984 0 0
MRK-003 + SCH772984 MRK-003 SCH772984 0 0
Navitoclax + SCH772984 Navitoclax SCH772984 0 0
Nilotinib + SCH772984 Nilotinib SCH772984 0 0
OSI-027 + SCH772984 OSI-027 SCH772984 0 0
Osimertinib + RAF709 + SCH772984 Osimertinib RAF709 SCH772984 0 0
Osimertinib + SCH772984 Osimertinib SCH772984 0 0
Osimertinib + SCH772984 + Trametinib Osimertinib SCH772984 Trametinib 0 0
Palbociclib + SCH772984 Palbociclib SCH772984 0 0
Panobinostat + SCH772984 Panobinostat SCH772984 0 0
Pembrolizumab + SCH772984 Pembrolizumab SCH772984 0 0
PF-04691502 + SCH772984 PF-04691502 SCH772984 0 0
PF-06873600 + SCH772984 PF-06873600 SCH772984 0 0
Pictilisib + SCH772984 Pictilisib SCH772984 0 0
Ralimetinib + SCH772984 Ralimetinib SCH772984 0 0
Repotrectinib + SCH772984 Repotrectinib SCH772984 0 0
Ridaforolimus + SCH772984 Ridaforolimus SCH772984 0 0
Saracatinib + SCH772984 SCH772984 Saracatinib 0 0
SCH772984 SCH772984 24 0
SCH772984 + Selpercatinib SCH772984 Selpercatinib 0 0
SCH772984 + Selumetinib SCH772984 Selumetinib 0 0
SCH772984 + SHP099 SCH772984 SHP099 0 0
SCH772984 + Temsirolimus SCH772984 Temsirolimus 0 0
SCH772984 + Tipifarnib SCH772984 Tipifarnib 2 0
SCH772984 + Trametinib SCH772984 Trametinib 0 0
SCH772984 + Vistusertib SCH772984 Vistusertib 0 0


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