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Drug Name Vistusertib
Trade Name
Synonyms AZD2014|AZD-2014
Drug Descriptions

Vistusertib (AZD2014) is an ATP-competitive inhibitor of mTOR, which may result in tumor growth inhibition (PMID: 23375793, PMID: 31707687).

DrugClasses mTOR Inhibitor 51
CAS Registry Number 1009298-59-2
NCIT ID C88329


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Acalabrutinib + Vistusertib Acalabrutinib Vistusertib 0 1
AZD4547 + Vistusertib AZD4547 Vistusertib 3 0
AZD8186 + Vistusertib AZD8186 Vistusertib 2 1
AZD9496 + Vistusertib AZD9496 Vistusertib 0 0
Durvalumab + Vistusertib Durvalumab Vistusertib 0 2
Fulvestrant + Palbociclib + Vistusertib Fulvestrant Palbociclib Vistusertib 0 1
Fulvestrant + Vistusertib Fulvestrant Vistusertib 0 1
Lorlatinib + Vistusertib Lorlatinib Vistusertib 0 0
MEDI-573 + Vistusertib MEDI-573 Vistusertib 1 0
MRTX849 + Vistusertib MRTX849 Vistusertib 0 0
Navitoclax + Vistusertib Navitoclax Vistusertib 0 1
Olaparib + Vistusertib Olaparib Vistusertib 0 1
Paclitaxel + Vistusertib Paclitaxel Vistusertib 3 0
SCH772984 + Vistusertib SCH772984 Vistusertib 0 0
Selumetinib + Vistusertib Selumetinib Vistusertib 0 0
Tamoxifen + Vistusertib Tamoxifen Vistusertib 0 0
Temozolomide + Vistusertib Temozolomide Vistusertib 1 0
Vistusertib Vistusertib 1 4
Vistusertib + WEHI-539 Vistusertib WEHI-539 1 0

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