Drug Detail


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Drug Name Ralimetinib
Trade Name
Synonyms LY2228820|LY-2228820|LY 2228820
Drug Descriptions

Ralimetinib (LY2228820) is a selective ATP competitive inhibitor of p38 MAPK alpha (MAPK14) and beta (MAPK11), which inhibits tumor growth (PMID: 26581242, PMID: 24356814, PMID: 31791552, PMID: 31707688).

DrugClasses p38-alpha Inhibitor 1
CAS Registry Number 862505-00-8
NCIT ID C143046


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Carboplatin + Gemcitabine + Ralimetinib Carboplatin Gemcitabine Ralimetinib 0 0
Prexasertib + Ralimetinib Prexasertib Ralimetinib 0 1
Ralimetinib Ralimetinib 0 1
Ralimetinib + SCH772984 Ralimetinib SCH772984 0 0

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