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Drug Name Linsitinib
Trade Name
Synonyms OSI-906
Drug Descriptions

Linsitinib (OSI-906) is a small molecule dual inhibitor of IGF-1R and IR, which leads to decreased tumor cell proliferation (PMID: 21425998, PMID: 31792037).

DrugClasses IGF-1R Inhibitor 17

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Therapy Name Drugs Efficacy Evidence Clinical Trials
ARS1620 + Everolimus + Linsitinib ARS1620 Everolimus Linsitinib 0 0
ARS1620 + Linsitinib ARS1620 Linsitinib 0 0
AZD8055 + Linsitinib AZD8055 Linsitinib 0 0
AZD8055 + Linsitinib + Trametinib AZD8055 Linsitinib Trametinib 0 0
BLZ945 + Linsitinib BLZ945 Linsitinib 0 0
Bortezomib + Dexamethasone + Linsitinib Bortezomib Dexamethasone Linsitinib 0 1
Crizotinib + Lapatinib + Linsitinib Crizotinib Lapatinib Linsitinib 0 0
Crizotinib + Linsitinib Crizotinib Linsitinib 0 0
Dabrafenib + Linsitinib Dabrafenib Linsitinib 0 0
Erlotinib + Linsitinib Erlotinib Linsitinib 0 0
Everolimus + Linsitinib Everolimus Linsitinib 0 0
Everolimus + Linsitinib + Trametinib Everolimus Linsitinib Trametinib 0 0
Gefitinib + Linsitinib Gefitinib Linsitinib 0 0
Gefitinib + Linsitinib + PHA-665752 Gefitinib Linsitinib PHA-665752 0 0
Linsitinib Linsitinib 2 0
Linsitinib + Midostaurin Linsitinib Midostaurin 0 0
Linsitinib + Palbociclib Linsitinib Palbociclib 0 0
Linsitinib + PF-4708671 Linsitinib PF-4708671 0 0
Linsitinib + Pictilisib Linsitinib Pictilisib 1 0
Linsitinib + Sapanisertib Linsitinib Sapanisertib 0 0
Linsitinib + Sapanisertib + Trametinib Linsitinib Sapanisertib Trametinib 0 0
Linsitinib + SCH772984 Linsitinib SCH772984 0 0
Linsitinib + Selumetinib Linsitinib Selumetinib 0 0
Linsitinib + Temsirolimus Linsitinib Temsirolimus 0 0
Linsitinib + Temsirolimus + Trastuzumab Linsitinib Temsirolimus Trastuzumab 0 0
Linsitinib + Torkinib Linsitinib Torkinib 0 0
Linsitinib + Torkinib + Trametinib Linsitinib Torkinib Trametinib 0 0


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