Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name PHA-665752
Trade Name
Synonyms PHA665752|PHA 665752
Drug Descriptions

PHA-665752 is a small molecule inhibitor of MET, which inhibits MET kinase activity and downstream signaling, potentially resulting in increased apoptosis and decreased proliferation and migration of tumor cells (PMID: 14612533, PMID: 29456739).

DrugClasses MET Inhibitor 59
CAS Registry Number 477575-56-7
NCIT ID NA

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Conteltinib + PHA-665752 Conteltinib PHA-665752 0 0
Gefitinib + Linsitinib + PHA-665752 Gefitinib Linsitinib PHA-665752 0 0
Gefitinib + PHA-665752 Gefitinib PHA-665752 0 0
PHA-665752 PHA-665752 1 0
PHA-665752 + Sonidegib PHA-665752 Sonidegib 0 0
PHA-665752 + Xentuzumab PHA-665752 Xentuzumab 0 0


Additional content available in CKB BOOST