Drug Detail


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Drug Name PHA-665752
Trade Name
Synonyms PHA665752|PHA 665752
Drug Descriptions

PHA-665752 is a small molecule inhibitor of MET, which inhibits MET kinase activity and downstream signaling, potentially resulting in increased apoptosis and decreased proliferation and migration of tumor cells (PMID: 14612533, PMID: 29456739).

DrugClasses MET Inhibitor 59
CAS Registry Number 477575-56-7


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Conteltinib + PHA-665752 Conteltinib PHA-665752 0 0
Gefitinib + Linsitinib + PHA-665752 Gefitinib Linsitinib PHA-665752 0 0
Gefitinib + PHA-665752 Gefitinib PHA-665752 0 0
PHA-665752 PHA-665752 1 0
PHA-665752 + Sonidegib PHA-665752 Sonidegib 0 0
PHA-665752 + Xentuzumab PHA-665752 Xentuzumab 0 0

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