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|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|PHA-665752||PHA665752|PHA 665752||MET Inhibitor 58||PHA-665752 is a small molecule inhibitor of MET, which inhibits MET kinase activity and downstream signaling, potentially resulting in increased apoptosis and decreased proliferation and migration of tumor cells (PMID: 14612533, PMID: 29456739).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|FGFR1 pos FGFR2 pos||hepatocellular carcinoma||no benefit||PHA-665752||Preclinical - Cell culture||Actionable||In a preclinical study, PHA-665752 treatment did not result in decreased colony formation or reduced phosphorylation levels of FGFR1 and FGFR2 in hepatocellular carcinoma cells in culture (PMID: 26351320).||26351320|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status||Covered Countries||Other Countries|