Drug Detail

Drug Name Xentuzumab
Trade Name
Synonyms BI 836845
Drug Descriptions

Xentuzumab (BI 836845) is a monoclonal antibody that binds to IGF-1 and IGF-2 and prevents binding to the IGF receptor (IGF-1R), resulting in decreased IGF-1R signaling (NCI Drug Dictionary).

DrugClasses IGF1/2 Antibody 2

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Abemaciclib + Anastrozole + Xentuzumab Abemaciclib Anastrozole Xentuzumab 0 1
Abemaciclib + Fulvestrant + Xentuzumab Abemaciclib Fulvestrant Xentuzumab 0 1
Abemaciclib + Letrozole + Xentuzumab Abemaciclib Letrozole Xentuzumab 0 1
Abemaciclib + Xentuzumab Abemaciclib Xentuzumab 0 1
Everolimus + Exemestane + Xentuzumab Everolimus Exemestane Xentuzumab 0 1
PHA-665752 + Xentuzumab PHA-665752 Xentuzumab 0 0
Xentuzumab Xentuzumab 0 1


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