Drug Detail


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Drug Name ARS1620
Trade Name
Synonyms ARS-1620
Drug Descriptions

ARS1620 is a covalent inhibitor of KRAS G12C, which may inhibit ERK activation and proliferation in tumor cells harboring KRAS G12C, particularly in combination with other targeted agents (PMID: 30327306, PMID: 29373830, PMID: 31776128).

DrugClasses KRAS G12C inhibitor 33
CAS Registry Number 1698055-85-4


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Therapy Name Drugs Efficacy Evidence Clinical Trials
ARS1620 ARS1620 0 0
ARS1620 + Everolimus ARS1620 Everolimus 0 0
ARS1620 + Everolimus + Linsitinib ARS1620 Everolimus Linsitinib 0 0
ARS1620 + Gefitinib ARS1620 Gefitinib 0 0
ARS1620 + Linsitinib ARS1620 Linsitinib 0 0
ARS1620 + Osimertinib ARS1620 Osimertinib 0 0
ARS1620 + Pictilisib ARS1620 Pictilisib 0 0

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