Drug Detail


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Drug Name YM-254890
Trade Name
Synonyms YM254890|YM 254890
Drug Descriptions

YM-254890 is a specific inhibitor of the G protein-coupled receptor, Gq (PMID: 31539242), that inhibits the exchange reaction of GDP/GTP by inhibiting the release of GDP (PMID: 20639466), and may lead to inhibition of cell proliferation and tumor formation (PMID: 33229459).

CAS Registry Number 568580-02-9


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Alpelisib + YM-254890 Alpelisib YM-254890 0 0
AXL1717 + YM-254890 AXL1717 YM-254890 0 0
Binimetinib + YM-254890 Binimetinib YM-254890 0 0
Linsitinib + YM-254890 Linsitinib YM-254890 0 0
Trametinib + YM-254890 Trametinib YM-254890 1 0
YM-254890 YM-254890 3 0

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