Drug Detail


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Drug Name AXL1717
Trade Name
Synonyms Picropodophyllin|PPP|Picropodophyllotoxin
Drug Descriptions

AXL1717 (picropodophyllin) inhibits IGF-1R, potentially leading to decreased tumor growth (PMID: 21875414, PMID: 31340850).

DrugClasses IGF-1R Inhibitor 17
CAS Registry Number 477-47-4
NCIT ID C87736


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Therapy Name Drugs Efficacy Evidence Clinical Trials
AXL1717 AXL1717 0 1
AXL1717 + Brigatinib AXL1717 Brigatinib 0 0
AXL1717 + Ceritinib AXL1717 Ceritinib 0 0
AXL1717 + Crizotinib AXL1717 Crizotinib 0 0
AXL1717 + YM-254890 AXL1717 YM-254890 0 0

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