Drug Detail

Drug Name Danusertib
Trade Name
Synonyms PHA-739358
Drug Descriptions

Danusertib (PHA-739358) is a pan-Aurora kinase with additional activity against ABL, FGFR1, RET, TRKA, and BCR-ABL, including the T315I mutant (PMID: 20072840, PMID: 18089710).

DrugClasses ABL1 Inhibitor 5 AURK Inhibitor (Pan) 11 BCR-ABL Inhibitor 24 FGFR1 Inhibitor 21 RET Inhibitor 36 TrkA Receptor Inhibitor 7

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Danusertib Danusertib 4 0
Danusertib + Fulvestrant Danusertib Fulvestrant 1 0
Danusertib + SCH772984 Danusertib SCH772984 0 0


Additional content available in CKB BOOST