Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name Saracatinib
Trade Name
Synonyms AZD0530
Drug Descriptions

Saracatinib (AZD0530) is a multi-kinase inhibitor with activity against ABL and SRC, which may block proliferation, metastasis, and survival in cancer cells (PMID: 19393585, PMID: 32398945).

DrugClasses BCR-ABL Inhibitor 31 SRC Inhibitor 31
CAS Registry Number 379231-04-6
NCIT ID C48378

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Afatinib + Saracatinib Afatinib Saracatinib 0 0
Cediranib + Saracatinib Cediranib Saracatinib 1 0
Ceritinib + Saracatinib Ceritinib Saracatinib 0 0
Dasatinib + Saracatinib Dasatinib Saracatinib 0 0
Docetaxel + Saracatinib Docetaxel Saracatinib 0 0
Enzalutamide + Saracatinib Enzalutamide Saracatinib 0 0
Gefitinib + PLX4720 + Saracatinib Gefitinib PLX4720 Saracatinib 1 0
Lapatinib + Saracatinib Lapatinib Saracatinib 0 0
Lorlatinib + Saracatinib Lorlatinib Saracatinib 2 0
Nilotinib + Saracatinib Nilotinib Saracatinib 0 0
Osimertinib + PF-573228 + Saracatinib Osimertinib PF-573228 Saracatinib 0 0
Osimertinib + Saracatinib Osimertinib Saracatinib 0 0
Ponatinib + Saracatinib Ponatinib Saracatinib 0 0
Saracatinib Saracatinib 3 1
Saracatinib + SCH772984 SCH772984 Saracatinib 0 0
Saracatinib + Selumetinib Saracatinib Selumetinib 0 0
Saracatinib + TAK-632 Saracatinib TAK-632 0 0
Saracatinib + Vemurafenib Saracatinib Vemurafenib 1 0


Additional content available in CKB BOOST