Drug Detail

Drug Name PLX4720
Trade Name
Synonyms
Drug Descriptions

PLX4720 is a 7-azaindole derivative and RAF kinase inhibitor with greater affinity for BRAF V600E than BRAF wild-type (PMID: 18287029).

DrugClasses BRAF Inhibitor 19

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Alpelisib + PLX4720 Alpelisib PLX4720 1 0
BI2536 + PLX4720 BI2536 PLX4720 1 0
Cediranib + PLX4720 Cediranib PLX4720 1 0
Cediranib + PLX4720 + Selumetinib Cediranib PLX4720 Selumetinib 1 0
Cetuximab + PLX4720 Cetuximab PLX4720 1 0
Crizotinib + PLX4720 Crizotinib PLX4720 0 0
Doxorubicin + PLX4720 Doxorubicin PLX4720 1 0
Erlotinib + PLX4720 Erlotinib PLX4720 1 0
Everolimus + PLX4720 Everolimus PLX4720 1 0
Foretinib + PLX4720 Foretinib PLX4720 0 0
Gefitinib + PLX4720 Gefitinib PLX4720 1 0
Imatinib + PLX4720 Imatinib PLX4720 1 0
MLN4924 + PLX4720 MLN4924 PLX4720 0 0
Navitoclax + PLX4720 Navitoclax PLX4720 1 0
NSC-87877 + PLX4720 NSC-87877 PLX4720 0 0
Pictilisib + PLX4720 PLX4720 Pictilisib 1 0
PLX4720 PLX4720 20 0
PLX4720 + Selumetinib PLX4720 Selumetinib 3 0
PLX4720 + SGX523 PLX4720 SGX523 0 0
PLX4720 + TAK-632 PLX4720 TAK-632 1 0
PLX4720 + Tivozanib PLX4720 Tivozanib 1 0
PLX4720 + Vorinostat PLX4720 Vorinostat 1 0


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