Drug Detail


Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name Cediranib
Trade Name
Synonyms AZD-2171|Recentin|AZD2171|AZD 2171
Drug Descriptions

Cediranib (AZD-2171) is an ATP-competitive inhibitor of all three vascular endothelial growth factor receptors (FLT1, KDR, and FLT4) and KIT, thereby blocking VEGF-signaling, angiogenesis, and tumor cell growth (PMID: 15899831, PMID: 24714778, PMID: 32444417).

DrugClasses KIT Inhibitor 57 VEGFR1 Inhibitor 6 VEGFR2 Inhibitor 37 VEGFR3 Inhibitor 6
CAS Registry Number 288383-20-0
NCIT ID C80867


  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")


  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Bevacizumab + Cediranib Bevacizumab Cediranib 0 0
Carboplatin + Cediranib Carboplatin Cediranib 0 0
Carboplatin + Cediranib + Paclitaxel Carboplatin Cediranib Paclitaxel 0 0
Cediranib Cediranib 14 5
Cediranib + Cisplatin + Gemcitabine Cediranib Cisplatin Gemcitabine 0 0
Cediranib + Cisplatin + Pemetrexed Disodium Cediranib Cisplatin Pemetrexed Disodium 0 1
Cediranib + Durvalumab Cediranib Durvalumab 0 4
Cediranib + Durvalumab + Olaparib Cediranib Durvalumab Olaparib 0 1
Cediranib + Gefitinib Cediranib Gefitinib 0 0
Cediranib + Lenalidomide Cediranib Lenalidomide 0 1
Cediranib + Lomustine Cediranib Lomustine 0 0
Cediranib + Olaparib Cediranib Olaparib 2 16
Cediranib + Olaparib + Triapine Cediranib Olaparib Triapine 0 0
Cediranib + PLX4720 Cediranib PLX4720 1 0
Cediranib + PLX4720 + Selumetinib Cediranib PLX4720 Selumetinib 1 0
Cediranib + Saracatinib Cediranib Saracatinib 1 0
Cediranib + Triapine Cediranib Triapine 0 0

Additional content available in CKB BOOST