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| Drug Name | Decitabine |
| Trade Name | Dacogen |
| Synonyms | 5-aza-2-deoxycytidine |
| Drug Descriptions |
Dacogen (decitabine) is cytidine analog that incorporates into DNA and forms covalent bonds with DNA methyltransferases (DNMTs), resulting in decreased DNMT activity and hypomethylation, and potentially leading to reduced tumor growth (PMID: 28159832, PMID: 25130173). Dacogen (decitabine) is FDA approved for use in patients with myelodysplastic syndromes (FDA.gov). |
| DrugClasses | DNMT inhibitor (Pan) 5 |
| CAS Registry Number | 2353-33-5 |
| NCIT ID | C981 |
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