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Drug Name Plerixafor
Trade Name Mozobil
Synonyms AMD3100
Drug Descriptions

Mozobil (plerixafor) inhibits CXCR4 and CXCL12-mediated cell signaling to influence tumor metastasis (PMID: 19641136, PMID: 16815309).

DrugClasses CXCR4 Inhibitor 15
CAS Registry Number 110078-46-1


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Bevacizumab + Plerixafor Bevacizumab Plerixafor 0 1
Bortezomib + Plerixafor Bortezomib Plerixafor 0 1
Carmustine + Filgrastim + Plerixafor + Temozolomide Carmustine Filgrastim Plerixafor Temozolomide 0 1
Cemiplimab + Plerixafor Cemiplimab Plerixafor 0 1
Cladribine + Cytarabine + Plerixafor Cladribine Cytarabine Plerixafor 0 1
Decitabine + Plerixafor Decitabine Plerixafor 0 1
Etoposide + Filgrastim + Plerixafor Etoposide Filgrastim Plerixafor 0 1
Filgrastim + Plerixafor Filgrastim Plerixafor 0 3
Ibrutinib + Plerixafor Ibrutinib Plerixafor 0 0
Pembrolizumab + Plerixafor Pembrolizumab Plerixafor 0 1
Plerixafor Plerixafor 0 9
Plerixafor + Temozolomide Plerixafor Temozolomide 0 1

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