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Drug Name Cemiplimab
Trade Name Libtayo
Synonyms REGN2810|SAR439684
Drug Descriptions

Libtayo (cemiplimab) is a human antibody that targets PD-1 (PDCD1) and prevents interaction with PD-L1 (CD274) and PD-L2 (PDCD1LG2), potentially resulting in increased anti-tumor immune response and decreased tumor growth (PMID: 28265006). Libtayo (cemiplimab) is FDA approved for use in patients with cutaneous squamous cell carcinoma, who are not not eligible for curative surgery or radiation (FDA.gov).

DrugClasses Immune Checkpoint Inhibitor 94 PD-L1/PD-1 antibody 63

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Carboplatin + Cemiplimab + Cyclophosphamide + Doxorubicin + Paclitaxel Carboplatin Cemiplimab Cyclophosphamide Doxorubicin Paclitaxel 0 1
Carboplatin + Cemiplimab + Docetaxel Carboplatin Cemiplimab Docetaxel 0 1
Carboplatin + Cemiplimab + Paclitaxel Carboplatin Cemiplimab Paclitaxel 0 1
Carboplatin + Cemiplimab + Pemetrexed Disodium Carboplatin Cemiplimab Pemetrexed Disodium 0 1
Cemiplimab Cemiplimab 1 19
Cemiplimab + Cyclophosphamide Cemiplimab Cyclophosphamide 0 1
Cemiplimab + Cyclophosphamide + Doxorubicin + Paclitaxel Cemiplimab Cyclophosphamide Doxorubicin Paclitaxel 0 1
Cemiplimab + Cyclophosphamide + Sargramostim Cemiplimab Cyclophosphamide Sargramostim 0 1
Cemiplimab + Dabrafenib + Trametinib Cemiplimab Dabrafenib Trametinib 0 1
Cemiplimab + Degarelix + Docetaxel + Leuprolide Cemiplimab Degarelix Docetaxel Leuprolide 0 1
Cemiplimab + Degarelix + Leuprolide Cemiplimab Degarelix Leuprolide 0 0
Cemiplimab + Docetaxel Cemiplimab Docetaxel 0 1
Cemiplimab + Everolimus + Prednisone Cemiplimab Everolimus Prednisone 0 1
Cemiplimab + INO-5401 + INO-9012 + Temozolomide Cemiplimab INO-5401 INO-9012 Temozolomide 0 1
Cemiplimab + Ipilimumab Cemiplimab Ipilimumab 0 4
Cemiplimab + ISA101b Cemiplimab ISA101b 0 1
Cemiplimab + Isatuximab Cemiplimab Isatuximab 0 2
Cemiplimab + JX-594 Cemiplimab JX-594 0 1
Cemiplimab + Odronextamab Cemiplimab Odronextamab 0 1
Cemiplimab + Plerixafor Cemiplimab Plerixafor 0 1
Cemiplimab + Poly ICLC Cemiplimab Poly ICLC 0 1
Cemiplimab + Prednisone + Sirolimus Cemiplimab Prednisone Sirolimus 0 1
Cemiplimab + REGN3767 Cemiplimab REGN3767 1 1
Cemiplimab + REGN4018 Cemiplimab REGN4018 0 1
Cemiplimab + REGN4659 Cemiplimab REGN4659 0 1
Cemiplimab + REGN5678 Cemiplimab REGN5678 0 1
Cemiplimab + RP1 Cemiplimab RP1 0 1
Cemiplimab + SAR439459 Cemiplimab SAR439459 0 1
Cemiplimab + SAR441000 Cemiplimab SAR441000 0 1
Cemiplimab + VSV-hIFNbeta-NIS Cemiplimab VSV-hIFNbeta-NIS 0 1


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