Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name Leuprolide
Trade Name Lupron
Synonyms Leuprorelin
Drug Descriptions

Lupron (leuprolide) is an agonist of gonadotropin releasing hormone (GnRH), which results decreased testosterone production in males and decreased estradiol production in females, potentially leading to decreased growth of androgen-positive tumors (NCI Drug Dictionary).

DrugClasses

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Abiraterone + Apalutamide + Leuprolide Abiraterone Apalutamide Leuprolide 0 3
Abiraterone + Apalutamide + Leuprolide + Prednisone Abiraterone Apalutamide Leuprolide Prednisone 0 1
Abiraterone + Atezolizumab + Leuprolide + Prednisone Abiraterone Atezolizumab Leuprolide Prednisone 0 1
Abiraterone + Leuprolide + Niraparib + Prednisone Abiraterone Leuprolide Niraparib Prednisone 0 1
Abiraterone + Leuprolide + Prednisone Abiraterone Leuprolide Prednisone 0 2
Apalutamide + Leuprolide Apalutamide Leuprolide 0 2
Azacitidine + Leuprolide + Tretinoin Azacitidine Leuprolide Tretinoin 0 1
Bicalutamide + Docetaxel + Flutamide + Goserelin + Leuprolide + Nilutamide Bicalutamide Docetaxel Flutamide Goserelin Leuprolide Nilutamide 0 1
Bicalutamide + Docetaxel + Leuprolide Bicalutamide Docetaxel Leuprolide 0 2
Bicalutamide + Flutamide + Goserelin + Leuprolide + Nilutamide Bicalutamide Flutamide Goserelin Leuprolide Nilutamide 0 1
Bicalutamide + HSV-Tk + Leuprolide + Valacyclovir Bicalutamide HSV-Tk Leuprolide Valacyclovir 0 1
Cemiplimab + Degarelix + Docetaxel + Leuprolide Cemiplimab Degarelix Docetaxel Leuprolide 0 1
Cemiplimab + Degarelix + Leuprolide Cemiplimab Degarelix Leuprolide 0 0
Enzalutamide + Leuprolide Enzalutamide Leuprolide 0 1
Leuprolide Leuprolide 0 35
Leuprolide + Radium Ra 223 dichloride Leuprolide Radium Ra 223 dichloride 0 1


Additional content available in CKB BOOST